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Jane Adams

Researcher at University of Massachusetts Boston

Publications -  48
Citations -  2676

Jane Adams is an academic researcher from University of Massachusetts Boston. The author has contributed to research in topics: Pregnancy & Teratology. The author has an hindex of 23, co-authored 48 publications receiving 2590 citations. Previous affiliations of Jane Adams include Boston Children's Hospital & Massachusetts Mental Health Center.

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Pattern of Malformations in the Children of Women Treated With Carbamazepine During Pregnancy

TL;DR: The similarity between the children exposed prenatally to carbamazepine and those with the fetal hydantoin syndrome is probably related to the fact that both drugs are metabolized through the arene oxide pathway and raises the possibility that it is the epoxide intermediate rather than the specific drug itself that is the teratogenic agent.
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Event-related potentials in schizophrenia: their biological and clinical correlates and new model of schizophrenic pathophysiology

TL;DR: A new model of at least one form of schizophrenic pathology is presented that proposes that positive symptoms of schizophrenia are related to limbic system pathology and in particular to a dysregulation of the NMDA form of excitatory amino acid transmission, potentiated by stress, and leading to cell damage and death due to 'excitotoxicity'.
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Too much of a good thing: retinoic acid as an endogenous regulator of neural differentiation and exogenous teratogen.

TL;DR: How the properties of RA as a neural induction agent and organizer of segmentation can explain the consequences of RA depletion and overexpression is shown.
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Collaborative Behavioral Teratology Study: results.

TL;DR: The design of the CBTS allowed evaluation of the reproducibility and detection sensitivity of these behavioral test methods, as well as the impact of early testing experience on later behavioral assessment, offspring sex differences in response levels and variability, and the contribution of litter-to-litter and animal- to-animal variation to behavioral measures in a standardized test protocol.