J
Jane Rogers
Researcher at Wellcome Trust Sanger Institute
Publications - 140
Citations - 99944
Jane Rogers is an academic researcher from Wellcome Trust Sanger Institute. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 69, co-authored 121 publications receiving 93619 citations. Previous affiliations of Jane Rogers include Wellcome Trust & John Innes Centre.
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Journal ArticleDOI
Co-duplication of olfactory receptor and MHC class I genes in the mouse major histocompatibility complex
Claire Amadou,Ruth Younger,Sarah Sims,Lucy Matthews,Jane Rogers,Attila Kumánovics,Andreas Ziegler,Stephan Beck,Kirsten Fischer Lindahl +8 more
TL;DR: It is found that MHC-linked OR loci share duplication with MHC class I loci, have duplicated extensively and are polymorphic, which revives questions about potential reciprocal influences acting on the dynamics and evolution of the H2 region and the H1-linked Or loci.
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Genomic anatomy of the Tyrp1 (brown) deletion complex
Ian M. Smyth,Laurens G. Wilming,Angela W. Lee,Martin S. Taylor,Phillipe Gautier,K F Barlow,Justine Wallis,Sancha Martin,Rebecca Glithero,Ben Phillimore,Sarah Pelan,Rob Andrew,Karen Holt,Ruth Taylor,Stuart McLaren,John Burton,J Bailey,Sarah Sims,Jan Squares,Bob Plumb,A Joy,Richard Gibson,James Gilbert,Elizabeth M. Hart,Gavin K. Laird,Jane E. Loveland,Jonathon Mudge,Charles A. Steward,David Swarbreck,Jennifer Harrow,Philip North,Nicholas Leaves,John Greystrong,Maria Coppola,Shilpa Manjunath,Mark Campbell,Mark Smith,Gregory Strachan,Calli Tofts,Esther Boal,Victoria Cobley,Giselle Hunter,Christopher Kimberley,Daniel Thomas,Lee Cave-Berry,Paul Weston,Marc Botcherby,Sharon White,Ruth Edgar,Sally H. Cross,Marjan Irvani,Holger Hummerich,Eleanor H. Simpson,Dabney K. Johnson,Patricia R. Hunsicker,Peter Little,Tim Hubbard,R Duncan Campbell,Jane Rogers,Ian J. Jackson +59 more
TL;DR: This study provides a molecular insight into the basis of several characterized mouse mutants, which will allow further dissection of this region by targeted or chemical mutagenesis.
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Insertional mutagenesis in mice deficient for p15Ink4b, p16Ink4a, p21Cip1, and p27Kip1 reveals cancer gene interactions and correlations with tumor phenotypes.
Jaap Kool,Anthony G. Uren,Carla Pedro Martins,Carla Pedro Martins,Daoud Sie,Jeroen de Ridder,Jeroen de Ridder,Geoffrey Turner,Geoffrey Turner,Miranda van Uitert,Konstantin Matentzoglu,Wendy Lagcher,Paul Krimpenfort,Jules Gadiot,Colin Pritchard,Jack Lenz,Anders H. Lund,Anders H. Lund,Jos Jonkers,Jane Rogers,Jane Rogers,David J. Adams,Lodewyk F. A. Wessels,Lodewyk F. A. Wessels,Anton Berns,Maarten van Lohuizen +25 more
TL;DR: High-throughput murine leukemia virus insertional mutagenesis screens in mice that are deficient for one or two CDK inhibitors show a novel use for insertional Mutagenesis data in prioritizing disease-associated genes that emerge from genome-wide association studies.
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Identification of a Structurally Distinct CD101 Molecule Encoded in the 950-kb Idd10 Region of NOD Mice
Carlos Penha-Gonçalves,Carolyn Moule,Luc J. Smink,Joanna M. M. Howson,Simon G. Gregory,Jane Rogers,Paul A. Lyons,Joseph J. Suttie,Christopher J. Lord,Laurence B. Peterson,John A. Todd,Linda S. Wicker +11 more
TL;DR: The gene encoding the EWI immunoglobulin subfamily member EWI-101 (Cd101) is suggested as the most likely Idd10 candidate because of the previously reported immune-associated properties of the human CD101 molecule.
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Novel sequencing strategy for repetitive DNA in a Drosophila BAC clone reveals that the centromeric region of the Y chromosome evolved from a telomere
Maria Mendez-Lago,Jadwiga Wild,S. Whitehead,Alan Tracey,Beatriz de Pablos,Jane Rogers,Waclaw Szybalski,Alfredo Villasante +7 more
TL;DR: A novel kind of transposon-based approach for sequencing highly repetitive DNA sequences in BAC clones that could be a universal approach to resolving the heterochromatic regions of eukaryotic genomes.