D
David Swarbreck
Researcher at Norwich Research Park
Publications - 79
Citations - 17638
David Swarbreck is an academic researcher from Norwich Research Park. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 32, co-authored 71 publications receiving 14927 citations. Previous affiliations of David Swarbreck include University of California, Los Angeles & Wellcome Trust Sanger Institute.
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Journal ArticleDOI
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project
Ewan Birney,John A. Stamatoyannopoulos,Anindya Dutta,Roderic Guigó,Thomas R. Gingeras,Elliott H. Margulies,Zhiping Weng,Michael Snyder,Emmanouil T. Dermitzakis,Robert E. Thurman,Michael S. Kuehn,Christopher M. Taylor,Shane Neph,Christoph M. Koch,Saurabh Asthana,Ankit Malhotra,Ivan Adzhubei,Jason A. Greenbaum,Robert M. Andrews,Paul Flicek,Patrick J. Boyle,Hua Cao,Nigel P. Carter,Gayle K. Clelland,Sean Davis,Nathan Day,Pawandeep Dhami,Shane C. Dillon,Michael O. Dorschner,Heike Fiegler,Paul G. Giresi,Jeff Goldy,Michael Hawrylycz,Andrew Haydock,Richard Humbert,Keith D. James,Brett E. Johnson,Ericka M. Johnson,Tristan Frum,Elizabeth Rosenzweig,Neerja Karnani,Kirsten Lee,Gregory Lefebvre,Patrick A. Navas,Fidencio Neri,Stephen C. J. Parker,Peter J. Sabo,Richard Sandstrom,Anthony Shafer,David Vetrie,Molly Weaver,Sarah Wilcox,Man Yu,Francis S. Collins,Job Dekker,Jason D. Lieb,Thomas D. Tullius,Gregory E. Crawford,Shamil R. Sunyaev,William Stafford Noble,Ian Dunham,Alexandre Reymond,Alexandre Reymond,Philipp Kapranov,Joel Rozowsky,Deyou Zheng,Robert Castelo,Adam Frankish,Jennifer Harrow,Srinka Ghosh,Albin Sandelin,Ivo L. Hofacker,Robert Baertsch,Damian Keefe,Sujit Dike,Jill Cheng,Heather A. Hirsch,Edward A. Sekinger,Julien Lagarde,Josep F. Abril,Josep F. Abril,Atif Shahab,Christoph Flamm,Christoph Flamm,Claudia Fried,Jörg Hackermüller,Jana Hertel,Manja Lindemeyer,Kristin Missal,Andrea Tanzer,Andrea Tanzer,Stefan Washietl,Jan O. Korbel,Olof Emanuelsson,Jakob Skou Pedersen,Nancy Holroyd,Ruth Taylor,David Swarbreck,Nicholas Matthews,Mark Dickson,Daryl J. Thomas,Matthew T. Weirauch,James G. R. Gilbert,Jorg Drenkow,Ian Bell,Xiaodong Zhao,Kandhadayar G. Srinivasan,Wing-Kin Sung,Hong Sain Ooi,Kuo Ping Chiu,Sylvain Foissac,Tyler Alioto,Michael R. Brent,Lior Pachter,Michael L. Tress,Alfonso Valencia,Siew Woh Choo,Chiou Yu Choo,Catherine Ucla,Caroline Manzano,Carine Wyss,Evelyn Cheung,Taane G. Clark,James B. Brown,Madhavan Ganesh,Sandeep Patel,Hari Tammana,Jacqueline Chrast,Charlotte N. Henrichsen,Chikatoshi Kai,Jun Kawai,Ugrappa Nagalakshmi,Jia Qian Wu,Zheng Lian,Jin Lian,Peter E. Newburger,Xueqing Zhang,Peter J. Bickel,John S. Mattick,Piero Carninci,Yoshihide Hayashizaki,Sherman M. Weissman,Tim Hubbard,Richard M. Myers,Jane Rogers,Peter F. Stadler,Peter F. Stadler,Peter F. Stadler,Todd M. Lowe,Chia-Lin Wei,Yijun Ruan,Kevin Struhl,Mark Gerstein,Stylianos E. Antonarakis,Yutao Fu,Eric D. Green,Ulas Karaoz,Adam Siepel,Adam Siepel,James Taylor,Laura A. Liefer,Kris A. Wetterstrand,Peter J. Good,Elise A. Feingold,Mark S. Guyer,Gregory M. Cooper,Gregory M. Cooper,George Asimenos,Colin N. Dewey,Minmei Hou,Sergey Nikolaev,Juan I. Montoya-Burgos,Ari Löytynoja,Simon Whelan,Fabio Pardi,Tim Massingham,Haiyan Huang,Nan Zhang,Nan Zhang,Ian Holmes,James C. Mullikin,Abel Ureta-Vidal,Benedict Paten,Michael Seringhaus,Deanna M. Church,Kate R. Rosenbloom,W. James Kent,Eric A. Stone,Serafim Batzoglou,Nick Goldman,Ross C. Hardison,David Haussler,Webb Miller,Arend Sidow,Nathan D. Trinklein,Zhengdong D. Zhang,Leah O. Barrera,Rhona K. Stuart,David C. King,Adam Ameur,Stefan Enroth,Mark Bieda,Jonghwan Kim,Akshay Bhinge,Nan Jiang,Jun Liu,Fei Yao,Vinsensius B. Vega,Charlie W.H. Lee,Patrick Ng,Annie Yang,Zarmik Moqtaderi,Zhou Zhu,Xiaoqin Xu,Sharon L. Squazzo,Matthew J. Oberley,David R. Inman,Michael A. Singer,Todd Richmond,Kyle J. Munn,Kyle J. Munn,Alvaro Rada-Iglesias,Ola Wallerman,Jan Komorowski,Joanna C. Fowler,Phillippe Couttet,Alexander W. Bruce,Oliver M. Dovey,Peter D. Ellis,Cordelia Langford,David A. Nix,Ghia Euskirchen,Stephen Hartman,Alexander E. Urban,Peter Kraus,Sara Van Calcar,Nate Heintzman,Tae Hoon Kim,Kun Wang,Chunxu Qu,Gary C. Hon,Rosa Luna,Christopher K. Glass,M. Geoff Rosenfeld,Shelley Force Aldred,Sara J. Cooper,Anason S. Halees,Jane M. Lin,Hennady P. Shulha,Xiaoling Zhang,Mousheng Xu,Jaafar N. Haidar,Yong Yu,Vishwanath R. Iyer,Roland Green,Claes Wadelius,Peggy J. Farnham,Bing Ren,Rachel A. Harte,Angie S. Hinrichs,Heather Trumbower,Hiram Clawson,Jennifer Hillman-Jackson,Ann S. Zweig,Kayla E. Smith,Archana Thakkapallayil,Galt P. Barber,Robert M. Kuhn,Donna Karolchik,Lluís Armengol,Christine P. Bird,Paul I.W. de Bakker,Andrew D. Kern,Nuria Lopez-Bigas,Joel D. Martin,Barbara E. Stranger,Abigail Woodroffe,Eugene Davydov,Antigone S. Dimas,Eduardo Eyras,Ingileif B. Hallgrímsdóttir,Julian L. Huppert,Michael C. Zody,Gonçalo R. Abecasis,Xavier Estivill,Gerard G. Bouffard,Xiaobin Guan,Nancy F. Hansen,Jacquelyn R. Idol,Valerie Maduro,Baishali Maskeri,Jennifer C. McDowell,Morgan Park,Pamela J. Thomas,Alice C. Young,Robert W. Blakesley,Donna M. Muzny,Erica Sodergren,David A. Wheeler,Kim C. Worley,Huaiyang Jiang,George M. Weinstock,Richard A. Gibbs,Tina Graves,Robert S. Fulton,Elaine R. Mardis,Richard K. Wilson,Michele Clamp,James Cuff,Sante Gnerre,David B. Jaffe,Jean L. Chang,Kerstin Lindblad-Toh,Eric S. Lander,Eric S. Lander,Maxim Koriabine,Mikhail Nefedov,Kazutoyo Osoegawa,Yuko Yoshinaga,Baoli Zhu,Pieter J. de Jong +320 more
TL;DR: Functional data from multiple, diverse experiments performed on a targeted 1% of the human genome as part of the pilot phase of the ENCODE Project are reported, providing convincing evidence that the genome is pervasively transcribed, such that the majority of its bases can be found in primary transcripts.
Journal ArticleDOI
Shifting the limits in wheat research and breeding using a fully annotated reference genome
Rudi Appels,Rudi Appels,Kellye Eversole,Nils Stein,Nils Stein,Catherine Feuillet,Beat Keller,Jane Rogers,Curtis J. Pozniak,Frédéric Choulet,Assaf Distelfeld,Jesse Poland,Gil Ronen,Andrew G. Sharpe,Omer Barad,Kobi Baruch,Gabriel Keeble-Gagnère,Martin Mascher,Gil Ben-Zvi,Ambre-Aurore Josselin,Axel Himmelbach,François Balfourier,Juan J. Gutierrez-Gonzalez,Matthew J. Hayden,Chushin Koh,Gary J. Muehlbauer,Raj K. Pasam,Etienne Paux,Philippe Rigault,Josquin Tibbits,Vijay K. Tiwari,Manuel Spannagl,Daniel Lang,Heidrun Gundlach,Georg Haberer,Klaus F. X. Mayer,Danara Ormanbekova,Verena M. Prade,Hana Šimková,Thomas Wicker,David Swarbreck,Hélène Rimbert,Marius Felder,Nicolas Guilhot,Gemy Kaithakottil,Jens Keilwagen,Philippe Leroy,Thomas Lux,Sven Twardziok,Luca Venturini,Angéla Juhász,Michael Abrouk,Iris Fischer,Cristobal Uauy,Philippa Borrill,Ricardo H. Ramirez-Gonzalez,Dominique Arnaud,Smahane Chalabi,Boulos Chalhoub,Boulos Chalhoub,Aron T. Cory,Raju Datla,Mark W. Davey,John Jacobs,Stephen J. Robinson,Burkhard Steuernagel,Fred van Ex,Brande B. H. Wulff,Moussa Benhamed,Abdelhafid Bendahmane,Lorenzo Concia,David Latrasse,Jan Bartoš,Arnaud Bellec,Hélène Bergès,Jaroslav Doležel,Zeev Frenkel,Bikram S. Gill,Abraham B. Korol,Thomas Letellier,Odd-Arne Olsen,Kuldeep Singh,Miroslav Valárik,Edwin A. G. van der Vossen,Sonia Vautrin,Song Weining,Tzion Fahima,Vladimir Glikson,Dina Raats,Jarmila Číhalíková,Helena Toegelová,Jan Vrána,Pierre Sourdille,Benoit Darrier,D. Barabaschi,Luigi Cattivelli,Pilar Hernández,Sergio Gálvez,Hikmet Budak,Jonathan D. G. Jones,Kamil Witek,Guotai Yu,Ian Small,Joanna Melonek,Ruonan Zhou,Tatiana Belova,Kostya Kanyuka,Robert King,Kirby T. Nilsen,Sean Walkowiak,Richard D. Cuthbert,Ron Knox,Krysta Wiebe,Daoquan Xiang,Antje Rohde,Timothy Golds,Jana Čížková,Bala Ani Akpinar,Sezgi Biyiklioglu,Liangliang Gao,Amidou N’Daiye,Marie Kubaláková,Jan Šafář,Françoise Alfama,Anne-Françoise Adam-Blondon,Raphael Flores,Claire Guerche,Mikaël Loaec,Hadi Quesneville,Janet A. Condie,Jennifer Ens,Ron MacLachlan,Yifang Tan,Adriana Alberti,Jean-Marc Aury,Valérie Barbe,Arnaud Couloux,Corinne Cruaud,Karine Labadie,Sophie Mangenot,Patrick Wincker,Patrick Wincker,Gaganpreet Kaur,Ming-Cheng Luo,Sunish K. Sehgal,Parveen Chhuneja,O. P. Gupta,Suruchi Jindal,Parampreet Kaur,Palvi Malik,Priti Sharma,Bharat Yadav,Nagendra K. Singh,Jitendra P. Khurana,Chanderkant Chaudhary,Paramjit Khurana,Vinod Kumar,Ajay Kumar Mahato,Saloni Mathur,Amitha Mithra Sevanthi,Naveen Sharma,Ram Sewak Singh Tomar,Kateřina Holušová,Ondřej Plíhal,Matthew D. Clark,Matthew D. Clark,Darren Heavens,George Kettleborough,Jon Wright,Barbora Balcárková,Yuqin Hu,Elena A. Salina,Nikolai V. Ravin,Nikolai V. Ravin,Konstantin G. Skryabin,Konstantin G. Skryabin,Alexey V. Beletsky,Vitaly V. Kadnikov,Andrey V. Mardanov,Michail A. Nesterov,Andrey L. Rakitin,Ekaterina M. Sergeeva,Hirokazu Handa,Hiroyuki Kanamori,Satoshi Katagiri,Fuminori Kobayashi,Shuhei Nasuda,Tsuyoshi Tanaka,Jianzhong Wu,Federica Cattonaro,Min Jiumeng,Karl G. Kugler,Matthias Pfeifer,Simen Rød Sandve,Xu Xun,Bujie Zhan,Jacqueline Batley,Philipp E. Bayer,David Edwards,Satomi Hayashi,Zuzana Tulpová,Paul Visendi,Licao Cui,Xianghong Du,Kewei Feng,Xiaojun Nie,Wei Tong,Le Wang +207 more
TL;DR: This annotated reference sequence of wheat is a resource that can now drive disruptive innovation in wheat improvement, as this community resource establishes the foundation for accelerating wheat research and application through improved understanding of wheat biology and genomics-assisted breeding.
Journal ArticleDOI
The Arabidopsis Information Resource (TAIR): improved gene annotation and new tools
Philippe Lamesch,Tanya Z. Berardini,Donghui Li,David Swarbreck,Christopher Wilks,Rajkumar Sasidharan,Robert J. Muller,Kate Dreher,Debbie L. Alexander,Margarita Garcia-Hernandez,Athikkattuvalasu S. Karthikeyan,Cynthia H. Lee,William D. Nelson,Larry Ploetz,Shanker Singh,April Wensel,Eva Huala +16 more
TL;DR: Recent developments include several new genome releases, progress on functional annotation of the genome and the release of several new tools including Textpresso for Arabidopsis which provides the capability to carry out full text searches on a large body of research literature.
Journal ArticleDOI
A physical, genetic and functional sequence assembly of the barley genome
Klaus F. X. Mayer,Robbie Waugh,Peter Langridge,Timothy J. Close,Roger P. Wise,Andreas Graner,Takashi Matsumoto,Kazuhiro Sato,Alan H. Schulman,Ruvini Ariyadasa,Daniela Schulte,Naser Poursarebani,Ruonan Zhou,Burkhard Steuernagel,Martin Mascher,Uwe Scholz,Bu-Jun Shi,Kavitha Madishetty,Jan T. Svensson,Prasanna R. Bhat,Matthew J. Moscou,Josh Resnik,Gary J. Muehlbauer,Pete E. Hedley,Hui Liu,Jenny Morris,Zeev Frenkel,Avraham Korol,Hélène Bergès,Stefan Taudien,Marius Felder,Marco Groth,Matthias Platzer,Axel Himmelbach,Stefano Lonardi,Denisa Duma,Matthew Alpert,Francesa Cordero,Francesa Cordero,Marco Beccuti,Gianfranco Ciardo,Yaqin Ma,Steve Wanamaker,Federica Cattonaro,Vera Vendramin,Simone Scalabrin,Slobodanka Radovic,Rod A. Wing,Michele Morgante,Thomas Nussbaumer,Heidrun Gundlach,Mihaela Martis,Jesse Poland,Matthias Pfeifer,Cédric Moisy,Jaakko Tanskanen,Andrea Zuccolo,Manuel Spannagl,Joanne Russell,Arnis Druka,David Marshall,Micha Bayer,David Swarbreck,Dharanya Sampath,Sarah Ayling,Melanie Febrer,Mario Caccamo,Tsuyoshi Tanaka,Steve Wannamaker,Thomas Schmutzer,John W. S. Brown,John W. S. Brown,Geoffrey B. Fincher,Nils Stein +73 more
TL;DR: An integrated and ordered physical, genetic and functional sequence resource that describes the barley gene-space in a structured whole-genome context and suggests that post-transcriptional processing forms an important regulatory layer.
Journal ArticleDOI
The DNA sequence of the human X chromosome
Mark T. Ross,Darren Grafham,Alison J. Coffey,Steven E. Scherer,Kirsten McLay,Donna M. Muzny,Matthias Platzer,Gareth R. Howell,Christine Burrows,Christine P. Bird,Adam Frankish,Frances L Lovell,Kevin L. Howe,Jennifer L. Ashurst,Robert S. Fulton,Ralf Sudbrak,Ralf Sudbrak,Gaiping Wen,Matthew C. Jones,Matthew E. Hurles,T. Daniel Andrews,Carol Scott,Stephen M. J. Searle,Juliane Ramser,Adam Whittaker,Rebecca Deadman,Nigel P. Carter,Sarah E. Hunt,Rui Chen,Andrew Cree,Preethi H. Gunaratne,Paul Havlak,Anne Hodgson,Michael L. Metzker,Stephen Richards,Graham Scott,David Steffen,Erica Sodergren,David A. Wheeler,Kim C. Worley,R Ainscough,K D Ambrose,M. Ali Ansari-Lari,Swaroop Aradhya,R I S Ashwell,A K Babbage,Claire L Bagguley,Andrea Ballabio,Ruby Banerjee,Gary E Barker,K F Barlow,Ian P. Barrett,Karen N Bates,David Beare,Helen Beasley,Oliver Beasley,Alfred Beck,Graeme Bethel,Karin Blechschmidt,Nicola Brady,Sarah Bray-Allen,Anne Bridgeman,Andrew Brown,Mary J. Brown,David Bonnin,Elspeth A. Bruford,Christian J. Buhay,Paula E. Burch,D C Burford,Joanne Burgess,Wayne Burrill,John Burton,Jackie Bye,C Carder,Laura Carrel,Joseph Chako,Joanne C Chapman,Dean Chavez,Ellson Y. Chen,Guan Chen,Yuan Chen,Zhijian J. Chen,Craig Chinault,Alfredo Ciccodicola,Sue Y Clark,Graham Clarke,Chris Clee,S. M. Clegg,Kerstin P. Clerc-Blankenburg,Karen Clifford,Vicky Cobley,Charlotte G. Cole,Jen S. Conquer,N Corby,Richard E Connor,Robert G. David,Joy Davies,Clay Davis,John M. Davis,Oliver Delgado,Denise R. DeShazo,Pawandeep Dhami,Yan Ding,Huyen Dinh,Steve Dodsworth,Heather R. Draper,Shannon Dugan-Rocha,Andrew Dunham,Matthew Dunn,K. James Durbin,Ireena Dutta,Tamsin Eades,Matthew Ellwood,Alexandra Emery-Cohen,Helen Errington,Kathryn L. Evans,Louisa Faulkner,Fiona Francis,John Frankland,Audrey Fraser,Petra Galgoczy,James G. R. Gilbert,Rachel Gill,Gernot Glöckner,Simon G. Gregory,Susan M. Gribble,C Griffiths,Russell J. Grocock,Yanghong Gu,Rhian Gwilliam,Cerissa Hamilton,E. Hart,Alicia Hawes,Paul Heath,Katja Heitmann,Steffen Hennig,Judith Hernandez,Bernd Hinzmann,Sarah Ho,Michael Hoffs,Phillip J Howden,Elizabeth J. Huckle,Jennifer Hume,Paul Hunt,Adrienne Hunt,Judith Isherwood,Leni S. Jacob,David W. Johnson,Sally Jones,Pieter J. de Jong,Shirin S. Joseph,Stephen Keenan,Susan H. Kelly,Joanne K Kershaw,Ziad Khan,Petra Kioschis,Sven Klages,Andrew J Knights,Anna Kosiura,Christie Kovar-Smith,Gavin K. Laird,Cordelia Langford,S Lawlor,Margaret A. Leversha,Lora Lewis,Wen Liu,Christine Lloyd,D. M. Lloyd,Hermela Loulseged,Jane E. Loveland,J Lovell,Ryan J. Lozado,Jing Lu,Rachael Lyne,Jie Ma,Manjula Maheshwari,Lucy Matthews,Jennifer McDowall,Stuart McLaren,Amanda McMurray,Patrick Meidl,Thomas Meitinger,Sarah Milne,George Miner,Shailesh L Mistry,Margaret Morgan,Sidney Morris,Ines Müller,James C. Mullikin,Ngoc Nguyen,Gabriele Nordsiek,Gerald Nyakatura,Christopher N O'Dell,Geoffery Okwuonu,Sophie Palmer,Richard Pandian,David Parker,Julia E. Parrish,Shiran Pasternak,Dina Patel,Alex V Pearce,D. Pearson,Sarah Pelan,Lesette Perez,K M Porter,Yvonne Ramsey,Kathrin Reichwald,Susan Rhodes,Kerry A Ridler,David Schlessinger,Mary G. Schueler,Harminder Sehra,Charles Shaw-Smith,Hua Shen,E Sheridan,Ratna Shownkeen,C. D. Skuce,Michelle Smith,Elizabeth C. Sotheran,Helen E. Steingruber,Charles A. Steward,Roy Storey,R Mark Swann,David Swarbreck,Paul E. Tabor,Stefan Taudien,Tineace Taylor,Brian Teague,Karen Thomas,Andrea Thorpe,Kirsten M. Timms,Alan Tracey,Steve Trevanion,A Tromans,Michele D'Urso,Daniel Verduzco,Donna Villasana,Lenee Waldron,Melanie M. Wall,Qiaoyan Wang,James T. Warren,Georgina Warry,Xuehong Wei,Anthony P. West,S. Whitehead,Mathew N Whiteley,Jane E. Wilkinson,David Willey,Gabrielle Williams,Leanne Williams,Angela Williamson,Helen Williamson,Laurens G. Wilming,Rebecca Woodmansey,Paul Wray,Jennifer Yen,Jingkun Zhang,Jianling Zhou,Huda Y. Zoghbi,Sara Zorilla,David Buck,Richard Reinhardt,Annemarie Poustka,André Rosenthal,Hans Lehrach,Alfons Meindl,Patrick Minx,LaDeana W. Hillier,Huntington F. Willard,Richard K. Wilson,Robert H. Waterston,Catherine M. Rice,M. Vaudin,Alan Coulson,David L. Nelson,George M. Weinstock,John Sulston,Richard Durbin,Tim Hubbard,Richard A. Gibbs,Stephan Beck,Jane Rogers,David R. Bentley +282 more
TL;DR: This analysis illustrates the autosomal origin of the mammalian sex chromosomes, the stepwise process that led to the progressive loss of recombination between X and Y, and the extent of subsequent degradation of the Y chromosome.