J
Jared M. Baeten
Researcher at University of Washington
Publications - 528
Citations - 23945
Jared M. Baeten is an academic researcher from University of Washington. The author has contributed to research in topics: Pre-exposure prophylaxis & Population. The author has an hindex of 69, co-authored 456 publications receiving 20152 citations. Previous affiliations of Jared M. Baeten include Harvard University & Harborview Medical Center.
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Journal ArticleDOI
Rationale and design of a multi-center, open-label, randomised clinical trial comparing HIV incidence and contraceptive benefits in women using three commonly-used contraceptive methods (the ECHO study).
G Justus Hofmeyr,Charles S. Morrison,Jared M. Baeten,Tsungai Chipato,Deborah Donnell,Peter Gichangi,Peter Gichangi,Nelly Mugo,Nelly Mugo,Kavita Nanda,Helen Rees,Petrus S. Steyn,Douglas Taylor,Echo Trial Team +13 more
TL;DR: The ECHO study is designed to provide robust evidence on the relative risks (HIV acquisition) and benefits (pregnancy prevention) between three effective contraceptive methods and has been conducted with extensive stakeholder engagement.
Journal ArticleDOI
DMPA and HIV: why we need a trial.
Jared M. Baeten,D Baron,Willard Cates,Connie Celum,Tsungai Chipato,S Chombes,D Donnell,Gichangi,J Hofmeyr,Charles S. Morrison,Nelly Mugo,Kavita Nanda,Thesla Palanee,Petrus S. Steyn,Douglas Taylor,Marleen Temmerman +15 more
TL;DR: The evidence, ethics and feasibility of a possible experimental design, and the quality of the current observational evidence, are considered.
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Terminal Effector CD8 T Cells Defined by an IKZF2+IL-7R- Transcriptional Signature Express FcγRIIIA, Expand in HIV Infection, and Mediate Potent HIV-Specific Antibody-Dependent Cellular Cytotoxicity.
Prossy Naluyima,Kerri G. Lal,Margaret C. Costanzo,Gustavo H. Kijak,Gustavo H. Kijak,Veronica D. Gonzalez,Kim Blom,Leigh Anne Eller,Leigh Anne Eller,Matthew Creegan,Matthew Creegan,Ting Hong,Dohoon Kim,Dohoon Kim,Thomas C. Quinn,Niklas K. Björkström,Hans-Gustaf Ljunggren,David Serwadda,Elly Katabira,Nelson K. Sewankambo,Ronald H. Gray,Jared M. Baeten,Nelson L. Michael,Fred Wabwire-Mangen,Merlin L. Robb,Merlin L. Robb,Diane L. Bolton,Diane L. Bolton,Johan K. Sandberg,Michael A. Eller +29 more
TL;DR: The data indicate that terminally differentiated effector CD8 T cells acquire enhanced innate cell-like characteristics during chronic viral infection and suggest that HIV-specific ADCC is a function CD9 T cells use to target HIV-infected cells.
Journal ArticleDOI
High-dose valacyclovir decreases plasma HIV-1 RNA more than standard-dose acyclovir in persons coinfected with HIV-1 and HSV-2: a randomized crossover trial.
Tara Perti,Misty Saracino,Jared M. Baeten,Christine Johnston,Kurt Diem,Negusse Ocbamichael,Meei Li Huang,Stacy Selke,Amalia Magaret,Lawrence Corey,Anna Wald +10 more
TL;DR: In this article, a randomized, open-label crossover trial of valacyclovir 1000 mg twice daily or acyclovirus 400 mg once daily for 12 weeks, followed by a 2-week washout, and then the alternate treatment arm for another 12 weeks.
Journal ArticleDOI
Host Genetic and Viral Determinants of HIV-1 RNA Set Point among HIV-1 Seroconverters from Sub-Saharan Africa
Romel D. Mackelprang,Mary Carrington,Mary Carrington,Katherine K. Thomas,James P. Hughes,James P. Hughes,Jared M. Baeten,Anna Wald,Carey Farquhar,Kenneth H. Fife,Mary S. Campbell,Saida Kapiga,Saida Kapiga,Xiaojiang Gao,James I. Mullins,Jairam R. Lingappa +15 more
TL;DR: Both innate and adaptive immune responses, together with plasma HIV-1 levels of the transmitting partner, explain almost half of the variation in viral load set point, an equilibrium between the virus and host responses that is predictive of later disease progression and transmission potential.