J
Jean-Christophe Leroux
Researcher at ETH Zurich
Publications - 320
Citations - 24325
Jean-Christophe Leroux is an academic researcher from ETH Zurich. The author has contributed to research in topics: Micelle & Drug carrier. The author has an hindex of 74, co-authored 307 publications receiving 21898 citations. Previous affiliations of Jean-Christophe Leroux include Delaware Biotechnology Institute & McGill University.
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Journal ArticleDOI
Block copolymer micelles: preparation, characterization and application in drug delivery.
Geneviève Gaucher,Marie-Hélène Dufresne,Vinayak Sant,Ning Kang,Dusica Maysinger,Jean-Christophe Leroux +5 more
TL;DR: The innovations in block copolymer synthesis, polymeric micelle preparation and characterization, as well as the relevance of these developments to the field of biomedical research are proposed.
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Novel injectable neutral solutions of chitosan form biodegradable gels in situ
Abdellatif Chenite,C Chaput,Dadong Wang,C Combes,Michael D. Buschmann,Caroline D. Hoemann,Jean-Christophe Leroux,B.L Atkinson,F Binette,A Selmani +9 more
TL;DR: This study reports for the first time the use of polymer/polyol salt aqueous solutions as gelling systems, suggesting the discovery of a prototype for a new family of thermosetting gels highly compatible with biological compounds.
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Polymeric micelles - a new generation of colloidal drug carriers.
TL;DR: This review examines the chemical nature of polymeric micelles as well as the methods used to characterize them with regard to drug delivery and potential medical applications, especially in cancer chemotherapy, are described and discussed.
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In situ-forming hydrogels--review of temperature-sensitive systems.
TL;DR: This manuscript focuses on aqueous polymeric solutions that form implants in situ in response to temperature change, generally from ambient to body temperature, and mainly reviews the characterization and use of polysaccharides, N-isopropylacrylamide copolymers, poly(ethylene oxide) (poloxamer) and itsCopolymers.
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Organogels and their use in drug delivery — A review
TL;DR: A global view of organogels is provided, with special emphasis on the interplay between the gelator's structural characteristics and the ensuing intermolecular interactions, for active agent administration via diverse routes such as transdermal, oral, and parenteral.