J
Jean-Denis Faure
Researcher at Université Paris-Saclay
Publications - 63
Citations - 3785
Jean-Denis Faure is an academic researcher from Université Paris-Saclay. The author has contributed to research in topics: Gene & Mutant. The author has an hindex of 30, co-authored 59 publications receiving 3267 citations. Previous affiliations of Jean-Denis Faure include Centre national de la recherche scientifique & Institut national de la recherche agronomique.
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Journal ArticleDOI
Reconstitution of Plant Alkane Biosynthesis in Yeast Demonstrates That Arabidopsis ECERIFERUM1 and ECERIFERUM3 Are Core Components of a Very-Long-Chain Alkane Synthesis Complex
Amélie Bernard,Frédéric Domergue,Frédéric Domergue,Stéphanie Pascal,Stéphanie Pascal,Reinhard Jetter,Charlotte Renne,Jean-Denis Faure,Richard P. Haslam,Johnathan A. Napier,René Lessire,René Lessire,Jérôme Joubès,Jérôme Joubès +13 more
TL;DR: A new model for alkane production is supported in which CER1 interacts with both CER3 and CYTB5 to catalyze the redox-dependent synthesis of VLC alkanes from VLC acyl-CoAs.
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Targeted interactomics reveals a complex core cell cycle machinery in Arabidopsis thaliana
Jelle Van Leene,Jens Hollunder,Dominique Eeckhout,Geert Persiau,Eveline Van De Slijke,Hilde Stals,Gert Van Isterdael,Aurine Verkest,Sandy Neirynck,Yelle Buffel,Stefanie De Bodt,Steven Maere,Kris Laukens,Anne Pharazyn,Paulo Cg Ferreira,Nubia Barbosa Eloy,Nubia Barbosa Eloy,Charlotte Renne,Christian Meyer,Jean-Denis Faure,Jens Steinbrenner,Jim Beynon,John C. Larkin,Yves Van de Peer,Pierre Hilson,Martin Kuiper,Lieven De Veylder,Harry Van Onckelen,Dirk Inzé,Erwin Witters,Erwin Witters,Geert De Jaeger +31 more
TL;DR: Plants have evolved a combinatorial toolkit consisting of at least 92 different CDK–cyclin complex variants, which strongly underscores the functional diversification among the large family of cyclins and reflects the pivotal role of cell cycle regulation in the developmental plasticity of plants.
Journal ArticleDOI
The very-long-chain hydroxy fatty acyl-CoA dehydratase PASTICCINO2 is essential and limiting for plant development.
Liên Bach,Louise V. Michaelson,Richard P. Haslam,Yannick Bellec,Lionel Gissot,Jessica Marion,Marco Da Costa,Jean Pierre Boutin,Martine Miquel,Frédérique Tellier,Frédéric Domergue,Jonathan E. Markham,Frédéric Beaudoin,Johnathan A. Napier,Jean-Denis Faure +14 more
TL;DR: It is demonstrated by in vivo bimolecular fluorescence complementation that PAS2 was specifically associated in the endoplasmic reticulum with the enoyl-CoA reductase CER10, the fourth enzyme of the elongase complex, indicating premature termination of fatty acid elongation and confirming the role of PAS 2 in this process.
Journal ArticleDOI
Selective gene dosage by CRISPR-Cas9 genome editing in hexaploid Camelina sativa
Céline Morineau,Yannick Bellec,Frédérique Tellier,Lionel Gissot,Zsolt Kelemen,Fabien Nogué,Jean-Denis Faure +6 more
TL;DR: Selective, targeted mutagenesis of the three delta‐12‐desaturase (FAD2) genes was achieved by CRISPR‐Cas9 gene editing, leading to reduced levels of polyunsaturated fatty acids and increased accumulation of oleic acid in the oil.
Journal ArticleDOI
Sphingolipids Containing Very-Long-Chain Fatty Acids Define a Secretory Pathway for Specific Polar Plasma Membrane Protein Targeting in Arabidopsis
Jonathan E. Markham,Diana Molino,Lionel Gissot,Yannick Bellec,Kian Hématy,Jessica Marion,Katia Belcram,Jean Christophe Palauqui,Béatrice Satiat-Jeunemaitre,Jean-Denis Faure +9 more
TL;DR: It is shown that Arabidopsis has two classes of ceramide synthases discriminating acyl chain length and also that very-long-acyl-chain sphingolipids are required for polar auxin transport in particular during lateral root emergence and a trafficking pathway with specific endomembrane compartments and polar auxIn transport protein cargoes is defined.