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Jean-Pierre Gorvel

Researcher at Aix-Marseille University

Publications -  239
Citations -  16211

Jean-Pierre Gorvel is an academic researcher from Aix-Marseille University. The author has contributed to research in topics: Brucella & Endosome. The author has an hindex of 67, co-authored 231 publications receiving 15005 citations. Previous affiliations of Jean-Pierre Gorvel include Centre national de la recherche scientifique & Aberystwyth University.

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Identification of Brucella spp. genes involved in intracellular trafficking.

Rose-May Delrue, +9 more
- 01 Jul 2001 - 
TL;DR: The preponderance of virB mutants demonstrates the importance of this secretion apparatus in the intracellular multiplication of B. melitensis and examines the intrACEllular fate of three VirB mutants in HeLa cells by immunofluorescence.
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What have we learned from brucellosis in the mouse model

María Jesús Grilló, +6 more
- 13 Apr 2012 - 
TL;DR: It is concluded that, when used properly, the mouse is a valuable brucellosis model and a useful virulence/attenuation index and is used in vaccine (Residual Virulence) quality control.
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Internal affairs: investigating the Brucella intracellular lifestyle.

Kristine von Bargen, +8 more
- 01 May 2012 - 
TL;DR: Understanding how Brucella molecules interplay with their host cell targets to modulate cellular functions and establish the intracellular niche will help unravel how this pathogen causes disease.
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An evolutionary strategy for a stealthy intracellular Brucella pathogen

Anna Martirosyan, +4 more
- 01 Mar 2011 - 
TL;DR: In this paper, the stealthy strategy used by Brucella to escape recognition of the innate immunity and the means by which this bacterium evades intracellular destruction are discussed.
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Bactericidal activity of Lys49 and Asp49 myotoxic phospholipases A2 from Bothrops asper snake venom--synthetic Lys49 myotoxin II-(115-129)-peptide identifies its bactericidal region

Leandro Páramo, +5 more
- 15 Apr 1998 - 
TL;DR: Bacterial LPS chimeras indicated that LPS is a relevant target for myotoxin II-(115-129)-peptide, which represents a group-II PLA2 with a direct bactericidal effect that is independent of an intrinsic enzymatic activity, but adscribed to the presence of a short cluster of basic/hydrophobic amino acids near its C-terminal loop.