J
Jean-Pierre Gorvel
Researcher at Aix-Marseille University
Publications - 239
Citations - 16211
Jean-Pierre Gorvel is an academic researcher from Aix-Marseille University. The author has contributed to research in topics: Brucella & Endosome. The author has an hindex of 67, co-authored 231 publications receiving 15005 citations. Previous affiliations of Jean-Pierre Gorvel include Centre national de la recherche scientifique & Aberystwyth University.
Papers
More filters
Journal Article
When intracellular pathogens invade the frontiers of cell biology and immunology.
TL;DR: The different strategies used by several pathogens are presented and the mechanisms elaborated by host cells from the immune system to eliminate the parasites discussed.
Journal ArticleDOI
Inactivation of formyltransferase (wbkC) gene generates a Brucella abortus rough strain that is attenuated in macrophages and in mice.
Thais Lourdes Santos Lacerda,Patrícia Gomes Cardoso,Leonardo A. de Almeida,Ilana Lopes Baratella da Cunha Camargo,Daniela Almeida Freitas Afonso,Cyntia G. M. C. Trant,Gilson Costa Macedo,Eleonora Campos,Silvio L. Cravero,Suzana P. Salcedo,Suzana P. Salcedo,Suzana P. Salcedo,Jean-Pierre Gorvel,Jean-Pierre Gorvel,Jean-Pierre Gorvel,Sergio C. Oliveira +15 more
TL;DR: It is demonstrated that Brucella wbkC is critical for LPS biosynthesis and full bacterial virulence in bone marrow-derived macrophages and in smooth vaccine RB51.
Journal ArticleDOI
Flow cytometric sorting and biochemical characterization of the late endosomal rab7-containing compartment
Stéphane Méresse,Pascale Andre,Zohair Mishal,Marc Barad,Nicole Brun,Michel Desjardins,Jean-Pierre Gorvel +6 more
TL;DR: Results show that the rab7‐containing vesicles are a component of the endocytic pathway that connects late endosomes and lysosome and in which precursor forms of lysOSomal hydrolases, segregated from their receptor, might be included.
Journal ArticleDOI
Activation of Mouse T Lymphocytes by a Monoclonal Antibody to a Developmentally Regulated Surface Aminopeptidase (THAM)
Philippe Naquet,I Vivier,Jean-Pierre Gorvel,Pieter Brekelmans,Marc Barad,Anne-Maire Bernard,Michel Pierres +6 more
TL;DR: Some of the features of a T-cell activating molecule (THAM) identified in the mouse model, which has been found to be associated to a neutral ectoaminopeptidase activity, are reviewed.
Journal ArticleDOI
Subcellular localization of class I (A,B,C) and class II (DR and DQ) MHC antigens in jejunal epithelium of children with coeliac disease.
TL;DR: The results of this report indicate that immunological mechanisms may play a prominent role in coeliac disease.