J
Jeanette L. Gehrig
Researcher at Washington University in St. Louis
Publications - 6
Citations - 412
Jeanette L. Gehrig is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Metagenomics & Gut flora. The author has an hindex of 3, co-authored 4 publications receiving 220 citations.
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Journal ArticleDOI
Effects of microbiota-directed foods in gnotobiotic animals and undernourished children
Jeanette L. Gehrig,Siddarth Venkatesh,Hao Wei Chang,Matthew C. Hibberd,Vanderlene L. Kung,Jiye Cheng,Robert Y. Chen,Sathish Subramanian,Carrie A. Cowardin,Martin Meier,David O'Donnell,Michael Talcott,Larry D. Spears,Clay F. Semenkovich,Bernard Henrissat,Bernard Henrissat,Richard J. Giannone,Robert L. Hettich,Olga Ilkayeva,Michael J. Muehlbauer,Christopher B. Newgard,Christopher S. Sawyer,Richard D. Head,Dmitry A. Rodionov,Dmitry A. Rodionov,Aleksandr A. Arzamasov,Aleksandr A. Arzamasov,Semen A. Leyn,Semen A. Leyn,Andrei L. Osterman,Iqbal Hossain,M Munirul Islam,Nuzhat Choudhury,Shafiqul Alam Sarker,Sayeeda Huq,Imteaz Mahmud,Ishita Mostafa,Mustafa Mahfuz,Michael J. Barratt,Tahmeed Ahmed,Jeffrey I. Gordon +40 more
TL;DR: Identifying ingredients in complementary foods, consumed during the transition from exclusive milk feeding to a fully weaned state, that increase the representation and expressed beneficial functions of growth-promoting bacterial taxa in the developing microbiota could provide an effective, affordable, culturally acceptable, and sustainable approach to treatment.
Journal ArticleDOI
A sparse covarying unit that describes healthy and impaired human gut microbiota development
Arjun S. Raman,Jeanette L. Gehrig,Siddarth Venkatesh,Hao Wei Chang,Matthew C. Hibberd,Sathish Subramanian,Gagandeep Kang,Pascal O. Bessong,Aldo A. M. Lima,Margaret Kosek,William A. Petri,Dmitry A. Rodionov,Dmitry A. Rodionov,Aleksandr A. Arzamasov,Aleksandr A. Arzamasov,Semen A. Leyn,Semen A. Leyn,Andrei L. Osterman,Sayeeda Huq,Ishita Mostafa,M Munirul Islam,Mustafa Mahfuz,Rashidul Haque,Tahmeed Ahmed,Michael J. Barratt,Jeffrey I. Gordon +25 more
TL;DR: A statistical workflow was developed to identify conserved bacterial taxon-taxon covariance in the gut communities of healthy members of a Bangladeshi birth cohort who provided fecal samples monthly, suggesting that the ecogroup network is a conserved general feature of microbiota organization.
Journal ArticleDOI
Diarrhea as a Potential Cause and Consequence of Reduced Gut Microbial Diversity Among Undernourished Children in Peru.
Saba Rouhani,Nicholas W. Griffin,Pablo Peñataro Yori,Jeanette L. Gehrig,Maribel Paredes Olortegui,Mery Siguas Salas,Dixner Rengifo Trigoso,Lawrence H. Moulton,Eric R. Houpt,Michael J. Barratt,Margaret Kosek,Margaret Kosek,Jeffrey I. Gordon +12 more
TL;DR: Persistent, severe growth faltering may reduce the gut microbiota's resistance and resilience to diarrhea, leading to greater losses of diversity and longer recovery times, which denotes an increased risk of future diarrheal disease and growthfaltering.
Journal ArticleDOI
Finding the right fit: evaluation of short-read and long-read sequencing approaches to maximize the utility of clinical microbiome data
Jeanette L. Gehrig,Daniel M. Portik,Mark D. Driscoll,Eric M. Jackson,Shreyasee Chakraborty,D. Gratalo,Meredith Ashby,Ricardo Valladares +7 more
TL;DR: Despite higher costs, both amplicon and metagenomic long-read approaches yielded added microbiome data value in the form of higher confidence taxonomic and functional resolution and improved recovery of microbial genomes compared to traditional short-read methodologies.
Posted ContentDOI
Improved Metagenomic Binning with Transformers
TL;DR: Experimental results on a publicly available metagenomic dataset show superior clustering for shorter contigs compared to traditionally used tetranucleotide frequency (TNF), reconstruction of up to 17% more high-precision genomes, and improved semantic understanding of contigs.