Jiye Cheng

TL;DR: The results reveal that transmissible and modifiable interactions between diet and microbiota influence host biology and that adiposity is transmissible from human to mouse and that it was associated with changes in serum levels of branched-chain amino acids.

TL;DR: The authors investigated the role of the gut microbiome in kwashiorkor, an enigmatic form of severe acute malnutrition that is the consequence of inadequate nutrient intake plus additional environmental insults, and found that RUTF produced a transient maturation of metabolic functions that regressed when administration of RUTF was stopped.

TL;DR: Preclinical models indicate a causal, microbiota-dependent relationship between sialylated bovine milk oligosaccharides (S-BMO) and growth promotion in children with undernutrition.

TL;DR: A method in which a clonally arrayed collection of cultured, sequenced bacteria was generated from one of several human fecal microbiota samples found to transmit a particular phenotype to recipient germ-free mice is described, which enables a systems-level understanding of microbial contributions to human biology.

TL;DR: Findings provide genetic and metabolic details of how this H2-consuming SRB shapes the responses of a microbiota to diet ingredients and a framework for examining how individuals lacking D. piger differ from those who harbor it.