S
Siddarth Venkatesh
Researcher at Washington University in St. Louis
Publications - 20
Citations - 1813
Siddarth Venkatesh is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Contact lens & Tetherin. The author has an hindex of 13, co-authored 20 publications receiving 1480 citations. Previous affiliations of Siddarth Venkatesh include Auburn University & Aaron Diamond AIDS Research Center.
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Journal ArticleDOI
Gut bacteria that prevent growth impairments transmitted by microbiota from malnourished children
Laura V. Blanton,Mark R. Charbonneau,Tarek Salih,Michael J. Barratt,Siddarth Venkatesh,Olga Ilkaveya,Sathish Subramanian,Mark J. Manary,Indi Trehan,Josh M Jorgensen,Yue-Mei Fan,Bernard Henrissat,Semen A. Leyn,Dmitry A. Rodionov,Andrei L. Osterman,Kenneth Maleta,Christopher B. Newgard,Per Ashorn,Kathryn G. Dewey,Jeffrey I. Gordon +19 more
TL;DR: These preclinical findings provide evidence that gut microbiota immaturity is causally related to childhood undernutrition and reveal that specific beneficial microbes could potentially be exploited to resolve undernutrition syndromes.
Journal ArticleDOI
Effects of microbiota-directed foods in gnotobiotic animals and undernourished children
Jeanette L. Gehrig,Siddarth Venkatesh,Hao Wei Chang,Matthew C. Hibberd,Vanderlene L. Kung,Jiye Cheng,Robert Y. Chen,Sathish Subramanian,Carrie A. Cowardin,Martin Meier,David O'Donnell,Michael Talcott,Larry D. Spears,Clay F. Semenkovich,Bernard Henrissat,Bernard Henrissat,Richard J. Giannone,Robert L. Hettich,Olga Ilkayeva,Michael J. Muehlbauer,Christopher B. Newgard,Christopher S. Sawyer,Richard D. Head,Dmitry A. Rodionov,Dmitry A. Rodionov,Aleksandr A. Arzamasov,Aleksandr A. Arzamasov,Semen A. Leyn,Semen A. Leyn,Andrei L. Osterman,Iqbal Hossain,M Munirul Islam,Nuzhat Choudhury,Shafiqul Alam Sarker,Sayeeda Huq,Imteaz Mahmud,Ishita Mostafa,Mustafa Mahfuz,Michael J. Barratt,Tahmeed Ahmed,Jeffrey I. Gordon +40 more
TL;DR: Identifying ingredients in complementary foods, consumed during the transition from exclusive milk feeding to a fully weaned state, that increase the representation and expressed beneficial functions of growth-promoting bacterial taxa in the developing microbiota could provide an effective, affordable, culturally acceptable, and sustainable approach to treatment.
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Zero-order therapeutic release from imprinted hydrogel contact lenses within in vitro physiological ocular tear flow.
TL;DR: For the first time, zero-order release of a small molecular weight therapeutic, ketotifen fumarate is demonstrated from molecularly imprinted hydrogels used as therapeutic contact lenses within a novel microfluidic device that simulates the volumetric flow rates, tear volume and tear composition of the eye.
Journal ArticleDOI
Biomimetic hydrogels for enhanced loading and extended release of ocular therapeutics.
TL;DR: The potential of biomimetic carriers to load significant amounts of ocular medication such as H(1)-antihistamines as well as to release a therapeutic dosage of drug in vitro in a controlled fashion for 5 days, with an even further extension in the presence of protein.
Journal ArticleDOI
A sparse covarying unit that describes healthy and impaired human gut microbiota development
Arjun S. Raman,Jeanette L. Gehrig,Siddarth Venkatesh,Hao Wei Chang,Matthew C. Hibberd,Sathish Subramanian,Gagandeep Kang,Pascal O. Bessong,Aldo A. M. Lima,Margaret Kosek,William A. Petri,Dmitry A. Rodionov,Dmitry A. Rodionov,Aleksandr A. Arzamasov,Aleksandr A. Arzamasov,Semen A. Leyn,Semen A. Leyn,Andrei L. Osterman,Sayeeda Huq,Ishita Mostafa,M Munirul Islam,Mustafa Mahfuz,Rashidul Haque,Tahmeed Ahmed,Michael J. Barratt,Jeffrey I. Gordon +25 more
TL;DR: A statistical workflow was developed to identify conserved bacterial taxon-taxon covariance in the gut communities of healthy members of a Bangladeshi birth cohort who provided fecal samples monthly, suggesting that the ecogroup network is a conserved general feature of microbiota organization.