Jeffrey L. Evelhoch

TL;DR: This pilot study suggests that simplified ratio methods such as SUVR can be used to quantify NFT binding and support further clinical development of 18F-MK-6240 for potential application in longitudinal studies.

TL;DR: In this paper, the T 1 measurement method (pulse sequence) conforms to the following three criteria at all points in the sensitive volume of the surface coil (i) the Z magnetization is consistently prepared to a nonequilibrium value at time zero This initial condition must be the same at the start of every evolution period (ii) after preparation, the magnetization was allowed to return toward thermal equilibrium during variable evolution periods τ (iii) a constant fraction of the z magnetization must then be sampled (observed) at the end of the evolution period

TL;DR: The results indicate that hyperglycemia induced by intraperitoneal glucose injection is effective in lowering the tumor pH of the murine RIF-1 tumor.

TL;DR: A method to estimate the AIF in rats is presented that derives an AIF from the time course of a tracer passing through a carotid chamber and the results of computer simulations indicate that a common AIF obtained in one set of animals can be used for perfusion estimations in another set of Animals if the tracer is delivered as a dose.

TL;DR: In this article, the authors proposed a level of evidence of collusion between the authors and the authors of this paper.Level of Evidence: 5.1.5.0.0