Jennifer L. Mitcham

TL;DR: High-throughput screening has revealed two new broadly neutralizing antibodies from a clade A–infected donor in Africa, which exhibit great potency and are able to neutralize a wide range of viruses from many different clades.

TL;DR: Analysis of neutralization by the full complement of anti-HIV broadly neutralizing monoclonal antibodies now available reveals that certain combinations of antibodies should offer markedly more favourable coverage of the enormous diversity of global circulating viruses than others and these combinations might be sought in active or passive immunization regimes.

TL;DR: In this article, compositions and methods for the therapy and diagnosis of cancer, particularly prostate cancer, are disclosed and illustrative compositions comprise one or more prostate-specific polypeptides, immunogenic portions thereof, polynucleotides that encode such polyps, antigen presenting cell that expresses such polypeptic, and T cells that are specific for cells expressing such polyptides.

TL;DR: In this paper, the authors present compositions and methods for the therapy and diagnosis of cancer, such as breast cancer, which may include one or more breast tumor proteins, immunogenic portions thereof, or polynucleotides that encode such portions.

TL;DR: It is suggested that viral M2e can elicit broadly cross-reactive and protective antibodies in humans, and recombinant forms of these human antibodies may provide useful therapeutic agents to protect against infection from a broad spectrum of influenza A strains.