J
Jennifer S. Chen
Researcher at Yale University
Publications - 30
Citations - 2135
Jennifer S. Chen is an academic researcher from Yale University. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 13, co-authored 27 publications receiving 1448 citations. Previous affiliations of Jennifer S. Chen include Harvard University.
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Journal ArticleDOI
Effects of moderate alcohol consumption on cognitive function in women
TL;DR: The data suggest that in women, up to one drink per day does not impair cognitive function and may actually decrease the risk of cognitive decline.
Journal ArticleDOI
Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection.
Jin Wei,Mia Madel Alfajaro,Peter C DeWeirdt,Ruth E Hanna,William J. Lu-Culligan,Wesley L. Cai,Madison S. Strine,Shang Min Zhang,Vincent R. Graziano,Cameron O. Schmitz,Jennifer S. Chen,Madeleine C. Mankowski,Renata B. Filler,Neal G. Ravindra,Victor Gasque,Fernando J. de Miguel,Ajinkya Patil,Ajinkya Patil,Huacui Chen,Kasopefoluwa Y. Oguntuyo,Laura Abriola,Yulia V. Surovtseva,Robert C. Orchard,Benhur Lee,Brett D. Lindenbach,Katerina Politi,David van Dijk,Cigall Kadoch,Cigall Kadoch,Matthew D. Simon,Qin Yan,John G. Doench,Craig B. Wilen +32 more
TL;DR: It is shown that small molecule antagonists of identified gene products inhibited SARS-CoV-2 infection in monkey and human cells, demonstrating the conserved role of these genetic hits across species.
Journal ArticleDOI
Identification of a T follicular helper cell subset that drives anaphylactic IgE.
Uthaman Gowthaman,Jennifer S. Chen,Biyan Zhang,William F. Flynn,Yisi Lu,Wenzhi Song,Julie Joseph,Jake A. Gertie,Lan Xu,Magalie A. Collet,Jessica D.S. Grassmann,Tregony Simoneau,David Y. Chiang,M. Cecilia Berin,Joe Craft,Jason S. Weinstein,Adam Williams,Stephanie C. Eisenbarth +17 more
TL;DR: It is hypothesized that a distinct but rare TFH cell population regulates the production of high-affinity IgE in allergic disease, and a model of dedicator of cytokinesis 8 deficiency causes a monogenic form of allergy associated with aberrant production of IgE.
Journal ArticleDOI
Type 2 diabetes and cognitive function in community-dwelling elderly women.
TL;DR: In these women, diabetes was related to lower scores on several aspects of cognitive function, and hypoglycemic therapy may ameliorate scores.
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High-dose antioxidant supplements and cognitive function in community-dwelling elderly women
TL;DR: The use of specific vitamin E supplements, but not specific vitamin C supplements, may be related to modest cognitive benefits in older women, and associations were strongest among women with low dietary intakes of alpha-tocopherol.