J
Jens C. Pruessner
Researcher at University of Konstanz
Publications - 298
Citations - 31823
Jens C. Pruessner is an academic researcher from University of Konstanz. The author has contributed to research in topics: Trier social stress test & Stressor. The author has an hindex of 81, co-authored 280 publications receiving 28326 citations. Previous affiliations of Jens C. Pruessner include Ludwig Maximilian University of Munich & McGill University.
Papers
More filters
Journal ArticleDOI
Two formulas for computation of the area under the curve represent measures of total hormone concentration versus time-dependent change
TL;DR: It is shown that depending on which formula is used, different associations with other variables may emerge, and it is recommended to employ both formulas when analyzing data sets with repeated measures.
Journal ArticleDOI
Free Cortisol Levels after Awakening: A Reliable Biological Marker for the Assessment of Adrenocortical Activity
Jens C. Pruessner,Oliver T. Wolf,Dirk H. Hellhammer,Angelika Buske-Kirschbaum,K. von Auer,Silke Jobst,F. Kaspers,Clemens Kirschbaum +7 more
TL;DR: Early morning cortisol levels can be a reliable biological marker for the individual's adrenocortical activity when measured repeatedly with strict reference to the time of awakening, in contrast to single assessments at fixed times.
Journal ArticleDOI
Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions
Torsten Klengel,Divya Mehta,Christoph Anacker,Monika Rex-Haffner,Jens C. Pruessner,Carmine M. Pariante,Thaddeus W.W. Pace,Kristina B. Mercer,Helen S. Mayberg,Bekh Bradley,Bekh Bradley,Charles B. Nemeroff,Florian Holsboer,Christine Heim,Christine Heim,Kerry J. Ressler,Kerry J. Ressler,Theo Rein,Elisabeth B. Binder +18 more
TL;DR: It is found that a functional polymorphism altering chromatin interaction between the transcription start site and long-range enhancers in the FK506 binding protein 5 gene increased the risk of developing stress-related psychiatric disorders in adulthood by allele-specific, childhood trauma–dependent DNA demethylation in functional glucocorticoid response elements of FKBP5.
Journal ArticleDOI
City living and urban upbringing affect neural social stress processing in humans.
Florian Lederbogen,Peter Kirsch,Leila Haddad,Fabian Streit,Heike Tost,Philipp Schuch,Stefan Wüst,Jens C. Pruessner,Marcella Rietschel,Michael Deuschle,Andreas Meyer-Lindenberg +10 more
TL;DR: It is shown that urban upbringing and city living have dissociable impacts on social evaluative stress processing in humans, and distinct neural mechanisms for an established environmental risk factor are identified.
Journal ArticleDOI
Burnout, perceived stress, and cortisol responses to awakening.
TL;DR: Sixty-six teachers from local public schools (42 womenand 24 men, mean age 42 6 5 years) were asked to sample saliva for cortisol analysis on 3 consecutive days as discussed by the authors.