J
Jeong Won Park
Researcher at University of California, Irvine
Publications - 11
Citations - 1164
Jeong Won Park is an academic researcher from University of California, Irvine. The author has contributed to research in topics: Regeneration (biology) & Axon. The author has an hindex of 10, co-authored 11 publications receiving 1081 citations. Previous affiliations of Jeong Won Park include Gwangju Institute of Science and Technology & Electronics and Telecommunications Research Institute.
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Journal ArticleDOI
Microfluidic culture platform for neuroscience research.
TL;DR: The microfluidic device provides a highly adaptable platform for neuroscience research and may find applications in modeling CNS injury and neurodegeneration.
Journal ArticleDOI
Presynaptic regulation of astroglial excitatory neurotransmitter transporter GLT1.
Yongjie Yang,Oguz Gozen,Andrew M. Watkins,Ileana Lorenzini,Angelo C. Lepore,Yuanzheng Gao,Svetlana Vidensky,Jean Brennan,David J. Poulsen,Jeong Won Park,Noo Li Jeon,Michael B. Robinson,Jeffrey D. Rothstein +12 more
TL;DR: It is shown that presynaptic terminals regulate astroglial synaptic functions, GLT1/EAAT2, via kappa B-motif binding phosphoprotein (KBBP), the mouse homolog of human heterogeneous nuclear ribonucleoprotein K (hnRNP K), which binds the GLT 1/EAat2 promoter.
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Endothelial cell migration in stable gradients of vascular endothelial growth factor A and fibroblast growth factor 2: effects on chemotaxis and chemokinesis.
Irmeli Barkefors,Sébastien Le Jan,Lars Jakobsson,Eduar Hejll,Gustav Carlson,Henrik Johansson,Jonas Jarvius,Jeong Won Park,Noo Li Jeon,Johan Kreuger +9 more
TL;DR: Investigation of endothelial cell migration in response to hill-shaped gradients of vascular endothelial growth factor A and fibroblast growth factor 2 using a novel microfluidic chemotaxis chamber suggests that chemotactic growth factor gradients may instruct endothelial cells to shift toward a nonmigratory phenotype when approaching the growth factor source.
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Generation of stable complex gradients across two-dimensional surfaces and three-dimensional gels
Bobak Mosadegh,Carlos P. Huang,Jeong Won Park,Hwa Sung Shin,Bong Geun Chung,Sun-Kyu Hwang,Kun-Hong Lee,Hyung J. Kim,James P. Brody,Noo Li Jeon +9 more
TL;DR: A new microfluidic approach is described that can be used to produce spatiotemporal gradients across two-dimensional surfaces and three-dimensional gels under flow-free conditions and fabricating an array of designs along the gradient-generating region allows for parallel analysis.
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A hybrid microfluidic-vacuum device for direct interfacing with conventional cell culture methods
TL;DR: This platform provides a simple yet versatile tool for incorporating the advantages of a microfluidic approach to biological assays without changing established tissue culture protocols.