J
Jessica Saben
Researcher at University of Colorado Denver
Publications - 40
Citations - 1379
Jessica Saben is an academic researcher from University of Colorado Denver. The author has contributed to research in topics: Medicine & Offspring. The author has an hindex of 15, co-authored 31 publications receiving 1003 citations. Previous affiliations of Jessica Saben include Anschutz Medical Campus & University of Colorado Hospital.
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Journal ArticleDOI
Maternal obesity is associated with a lipotoxic placental environment.
Jessica Saben,Forrest Lindsey,Ying Zhong,Keshari M. Thakali,Thomas M. Badger,Aline Andres,Horacio Gomez-Acevedo,Kartik Shankar +7 more
TL;DR: RNA-sequencing on term placenta from obese women indicates that maternal obesity leads to a lipotoxic placental environment that is associated with decreased regulators of angiogenesis and increased markers of inflammation and oxidative stress.
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Maternal metabolic syndrome programs mitochondrial dysfunction via germline changes across three generations
Jessica Saben,Anna L. Boudoures,Zeenat Asghar,Alysha Thompson,Andrea M. Drury,Wendy Zhang,Maggie M.-Y. Chi,Andrew Cusumano,Suzanne M. Scheaffer,Kelle H. Moley +9 more
TL;DR: The results indicate that maternal programming of metabolic disease can be passed through the female germline and that the transfer of aberrant oocyte mitochondria to subsequent generations may contribute to the increased risk for developing insulin resistance.
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Acute Illness Associated With Cannabis Use, by Route of Exposure: An Observational Study
Andrew A. Monte,Shelby K. Shelton,Eleanor Mills,Jessica Saben,Andrew Hopkinson,Brandon J. Sonn,Michael Devivo,Tae Chang,Jacob Fox,Cody Brevik,Kayla Williamson,Diana Abbott +11 more
TL;DR: In this paper, the authors describe and compare adult emergency department (ED) visits related to edible and inhaled cannabis exposure, and find that visits attributable to inhaled consumption are more frequent than those attributable to edibles, although the latter is associated with more acute psychiatric visits and more ED visits than expected.
Journal ArticleDOI
Diet-induced obesity impairs endometrial stromal cell decidualization: a potential role for impaired autophagy
J.S. Rhee,Jessica Saben,Allyson L. Mayer,M. Schulte,Zeenat Asghar,Claire S Stephens,Maggie M.-Y. Chi,Kelle H. Moley +7 more
TL;DR: Diet-induced obesity impairs endometrial stromal cell (ESC) decidualization in obese women, and mice exposed to an HF/HS diet became obese and metabolically impaired.
Journal ArticleDOI
Glucose transporter 8 (GLUT8) mediates fructose-induced de novo lipogenesis and macrosteatosis.
TL;DR: It is demonstrated that GLUT8 is a cell surface-localized transporter and thatGLUT8 overexpression or GLUT 8 shRNA-mediated gene silencing significantly induces and blocks radiolabeled fructose uptake in cultured hepatocytes.