J
Jian Luo
Researcher at East China Normal University
Publications - 67
Citations - 3533
Jian Luo is an academic researcher from East China Normal University. The author has contributed to research in topics: Osteoclast & Metastasis. The author has an hindex of 31, co-authored 67 publications receiving 2952 citations. Previous affiliations of Jian Luo include Second Military Medical University & Hunan Normal University.
Papers
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Journal ArticleDOI
ZNF411, a novel KRAB-containing zinc-finger protein, suppresses MAP kinase signaling pathway.
Hui Liu,Chuanbing Zhu,Jian Luo,Yuequn Wang,Dali Li,Yongqing Li,Junmei Zhou,Wuzhou Yuan,Ying Ou,Mingyao Liu,Xiushan Wu +10 more
TL;DR: Results indicate that ZNF411 is a member of the zinc-finger transcription factor family and may be involved in the heart development, and it probably works as a negative regulator in MAPK signaling pathway.
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Inhibition of Osteoclastogenesis and Bone Resorption in vitro and in vivo by a prenylflavonoid xanthohumol from hops
Jing Li,Li Zeng,Juan Xie,Juan Xie,Zhiying Yue,Huayun Deng,Xueyun Ma,Chunbing Zheng,Xiushan Wu,Jian Luo,Mingyao Liu,Mingyao Liu +11 more
TL;DR: It is demonstrated that xanthohumol inhibits osteoclastogenesis and bone resorption through RANK/TRAF6 signaling pathways and could be a promising drug candidate in the treatment of osteOClast-related diseases such as postmenopausal osteoporosis.
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Optimization of 2-(3-(arylalkyl amino carbonyl) phenyl)-3-(2-methoxyphenyl)-4-thiazolidinone derivatives as potent antitumor growth and metastasis agents.
Jing Wu,Linxi Yu,Feifei Yang,Jingjie Li,Peng Wang,Wenbo Zhou,Liwen Qin,Yunqi Li,Jian Luo,Zhengfang Yi,Mingyao Liu,Yihua Chen +11 more
TL;DR: Results suggested that the new series of 2-(3-(arylalkyl amino carbonyl)phenyl)-3-(2-methoxyphenyl)-4-thiazolidinone derivatives could be regarded and developed as novel highly potential anticancer agents in the future.
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Inhibition of transcriptional activities of AP-1 and c-Jun by a new zinc finger protein ZNF394.
Chunxia Huang,Yuequn Wang,Dali Li,Yongqing Li,Jian Luo,Wuzhou Yuan,Ying Ou,Chuanbing Zhu,Yuejuan Zhang,Zhi Wang,Mingyao Liu,Xiushan Wu +11 more
TL;DR: Overexpression of ZNF394 in the cell inhibits the transcriptional activities of c-Jun and AP-1 reporters, suggesting that ZNF395 is a new transcriptional repressor in mitogen-activated protein kinase signaling pathways and may play an important role in cardiac development and/or cardiac function.
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Plumbagin inhibits breast tumor bone metastasis and osteolysis by modulating the tumor-bone microenvironment.
Zhenxi Li,J Xiao,Xian Wu,W Li,Zhengfeng Yang,J Xie,Lei Xu,X Cai,Z Lin,W Guo,Jian Luo,Mingyao Liu +11 more
TL;DR: It is demonstrated that plumbagin inhibits breast tumor bone metastasis and osteolysis by modulating the tumor-bone microenvironment and that plumberagin may serve as a novel agent in the treatment of tumorBone metastasis.