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Jianyong Han

Researcher at University of Minnesota

Publications -  29
Citations -  805

Jianyong Han is an academic researcher from University of Minnesota. The author has contributed to research in topics: Induced pluripotent stem cell & Embryonic stem cell. The author has an hindex of 12, co-authored 29 publications receiving 583 citations. Previous affiliations of Jianyong Han include China Agricultural University & Genome Institute of Singapore.

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Generation of induced pluripotent stem cells from bovine embryonic fibroblast cells

TL;DR: The first establishment of bovine iPS cells using defined transcription factors and a modified culture medium is reported, which can be used to produce viable mice through tetraploid complementation and several mammalian species have been successfully generated.
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Specific gene-regulation networks during the pre-implantation development of the pig embryo as revealed by deep sequencing

TL;DR: The results provide a resource for pluripotent stem cell engineering and for understanding pig development and revealed that pig and mouse pre-implantation embryos share regulatory networks during the first lineage segregation and primitive endoderm differentiation, but not during ectoderm commitment.
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Implantation initiation of self-assembled embryo-like structures generated using three types of mouse blastocyst-derived stem cells

TL;DR: A nonadherent-suspension-shaking system to generate self-assembled embryo-like structures (ETX-embryoids), which can initiate an implantation response and exhibit lumenogenesis, asymmetric patterns of gene expression for markers of mesoderm and primordial germ cell precursors, and formation of anterior visceral endoderm-like tissues.
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Bovine lineage specification revealed by single-cell gene expression analysis from zygote to blastocyst

TL;DR: Gene expression analysis of single blastomeres from zygote to blastocyst sheds light on the early cell fate determination in bovine preimplantation embryos and offers theoretical support for deriving bovines embryonic stem cells.