T
Tianzhi Chen
Researcher at University of Minnesota
Publications - 5
Citations - 97
Tianzhi Chen is an academic researcher from University of Minnesota. The author has contributed to research in topics: Embryonic stem cell & Induced pluripotent stem cell. The author has an hindex of 1, co-authored 3 publications receiving 44 citations.
Papers
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Journal ArticleDOI
Implantation initiation of self-assembled embryo-like structures generated using three types of mouse blastocyst-derived stem cells
Shaopeng Zhang,Tianzhi Chen,Naixin Chen,Dengfeng Gao,Bingbo Shi,Shuangbo Kong,Rachel West,Ye Yuan,Minglei Zhi,Qingqing Wei,Jinzhu Xiang,Haiyuan Mu,Liang Yue,Xiaohua Lei,Xuepeng Wang,Liang Zhong,Hui Liang,Suying Cao,Juan Carlos Izpisua Belmonte,Haibin Wang,Jianyong Han,Jianyong Han +21 more
TL;DR: A nonadherent-suspension-shaking system to generate self-assembled embryo-like structures (ETX-embryoids), which can initiate an implantation response and exhibit lumenogenesis, asymmetric patterns of gene expression for markers of mesoderm and primordial germ cell precursors, and formation of anterior visceral endoderm-like tissues.
Journal ArticleDOI
Generation and characterization of stable pig pregastrulation epiblast stem cell lines.
Minglei Zhi,Jinying Zhang,Qianzi Tang,Dawei Yu,Shuai Gao,Dengfeng Gao,Pengliang Liu,Jianxiong Guo,Tang Hai,Jie Gao,Suying Cao,Zimo Zhao,Chongyang Li,Xiaogang Weng,Mengnan He,Tianzhi Chen,Yingjie Wang,Keren Long,Deling Jiao,Guanglei Li,Jiaman Zhang,Yan Liu,Yu Lin,Daxin Pang,Qianqian Zhu,Naixin Chen,Jingjing Huang,Xinze Chen,Yixuan Yao,Jingcang Yang,Zicong Xie,Xianya Huang,Mengxin Liu,Ran Zhang,Qiuyan Li,Yiliang Miao,Jianhui Tian,Xingxu Huang,Hongsheng Ouyang,Bofeng Liu,Wei Xie,Qi Zhou,Hong-Jiang Wei,Zhonghua Liu,Caihong Zheng,Mingzhou Li,Jianyong Han +46 more
TL;DR: In this article, a large-scale single-cell transcriptome analysis of pig embryos from embryonic day (E) 0 to E14, specifically, the tracing of pluripotency changes during epiblast development, was performed.
Patent
Suspension shaking co-culture method and special compositions thereof for preparing reconstructed embryo
TL;DR: In this paper, a suspension shaking co-culture method and special compositions thereof for preparing a reconstructed embryo are described. But the method is not suitable for the preparation of embryos in the real world.
Journal ArticleDOI
Nanos3 knockout pigs to model transplantation and reconstruction of the germline
Jing Wang,Jilong Ren,Qingwei Wang,Chongyang Li,Zhiqiang Han,Tianzhi Chen,Guihai Feng,Jing Zhang,Jianyong Han,Qi Zhou,Wei Li,Dawei Yu,Tang Hai +12 more
TL;DR: In this article , the authors used spermatogonial stem cell transplantation (SSCT) to protect the germplasm via embryo transfer between male donors and recipients, which is one method to preserve these valuable germlines and genetic resources.
Journal ArticleDOI
Generation of stable integration-free pig induced pluripotent stem cells under chemically defined culture condition.
Qianqian Zhu,Fengliao Wang,Dengfeng Gao,Jie Gao,Guilin Li,Deling Jiao,Gaoxiang Zhu,Kaixiang Xu,Jianxiong Guo,Tianzhi Chen,Suying Cao,Ming Cai Zhi,Jinying Zhang,Yingjie Wang,Danru Zhang,Hong Wei,Jianyong Han +16 more
TL;DR: In this article , an efficient induction system for exogenous gene-independent pig induced pluripotent stem cells (iPSCs) under chemically defined culture condition was established for generation of stable pig pre-gastrulation epiblast stem cells.