J
Jihwan Park
Researcher at University of Pennsylvania
Publications - 53
Citations - 3736
Jihwan Park is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Kidney disease & Kidney. The author has an hindex of 23, co-authored 45 publications receiving 2125 citations. Previous affiliations of Jihwan Park include Gwangju Institute of Science and Technology & Pohang University of Science and Technology.
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DNMT1 in Six2 progenitor cells is essential for transposable element silencing and kidney development
Szu-Yuan Li,Szu-Yuan Li,Jihwan Park,Kiwung Chung,Rojesh Shrestha,Matthew B. Palmer,Katalin Susztak +6 more
TL;DR: Genome-wide cytosine methylation and gene expression profiling showed that Dnmt1-mediated DNA methylation is essential for kidney development by preventing regression of progenitor cells into a primitive undifferentiated state and demethylation of transposable elements.
Journal ArticleDOI
DDM1-mediated gene body DNA methylation is associated with inducible activation of defense-related genes in Arabidopsis
Seungchul Lee,Jaemyung Choi,Jihwan Park,Chang Pyo Hong,Dae-Ock Choi,Soeun Han,Kyu-Ri Choi,Tae-Young Roh,Dae-Ryong Hwang,Il Doo Hwang +9 more
TL;DR: In this paper , the role of gene body methylation (GBM) in defense responses to pathogen infection was investigated in Arabidopsis plants, and it was shown that DDM1-mediated GBM provides a possible regulatory axis for plants to modulate the inducibility of the immune response.
Journal ArticleDOI
Dawn-to-dusk dry fasting induces anti-atherosclerotic, anti-inflammatory, and anti-tumorigenic proteome in peripheral blood mononuclear cells in subjects with metabolic syndrome
Ayse L. Mindikoglu,Jihwan Park,Antone R. Opekun,Mustafa M. Abdulsada,Zoe R. Wilhelm,Prasun K. Jalal,Sridevi Devaraj,Sung Yun Jung +7 more
TL;DR: In this paper , the authors determined whether 4-week dawn-to-dusk dry fasting would induce favorable changes in peripheral blood mononuclear cells (PBMC) proteome in subjects with metabolic syndrome.
Journal ArticleDOI
Histamine Signaling Is Essential for Tissue Macrophage Differentiation and Suppression of Bacterial Overgrowth in the Stomach
Kwang H. Kim,Jihwan Park,Yejin Cho,Soo Young Cho,Buhyun Lee,Haengdueng Jeong,Yura Lee,Ja Woon Yi,Ye-Sung Oh,Jin-Jae Lee,Timothy C. Wang,K. Lim,Ki Taek Nam +12 more
TL;DR: In this article , the role of histamine in mediating macrophage differentiation and maintaining stomach homeostasis was investigated using histidine decarboxylase knockout mice with hypertrophic gastropathy.
Journal ArticleDOI
Increased levels of endogenous retroviruses trigger fibroinflammation and play a role in kidney disease development
Poonam Dhillon,Kelly Mulholland,Hailong Hu,Jihwan Park,Xin Sheng,Amin Abedini,Hongbo Liu,Allison Vassalotti,Junnan Wu,Katalin Susztak +9 more
TL;DR: In this article , a comprehensive RNA-sequencing of control and diseased kidney from human and mouse disease models indicated higher expression of transposable elements (TEs) and endogenous retroviruses (ERVs) in diseased kidneys.