scispace - formally typeset
J

Jin-Soo Kim

Researcher at Seoul National University

Publications -  308
Citations -  26566

Jin-Soo Kim is an academic researcher from Seoul National University. The author has contributed to research in topics: CRISPR & Genome editing. The author has an hindex of 66, co-authored 264 publications receiving 21375 citations. Previous affiliations of Jin-Soo Kim include UPRRP College of Natural Sciences & Korea University of Science and Technology.

Papers
More filters
Journal ArticleDOI

Mouse genetics: Catalogue and scissors

TL;DR: The recent achievement of IKMC is introduced, the significance of ZFN/TALEN technology in mouse genetics is evaluated, and new technologies, adopting zinc-finger nucleases (ZFNs) or Transcription Activator-Like Effector (TALE) Nucleases (TALens) to edit the mouse genome are evaluated.
Journal ArticleDOI

dCas9-mediated nanoelectrokinetic direct detection of target gene for liquid biopsy

TL;DR: Conclusively, the proposed dCas9-mediated genetic detection methodology based on ICP would provide rapid and accurate micro/nanofluidic platform of liquid biopsies for disease diagnostics.
Journal ArticleDOI

Long-Term Effects of In Vivo Genome Editing in the Mouse Retina Using Campylobacter jejuni Cas9 Expressed via Adeno-Associated Virus.

TL;DR: In this article, the smallest Cas9 ortholog from Campylobacter jejuni (CjCas9) targeted to Hif1a and delivered in an adeno-associated virus (AAV) vector, effectively suppressed pathological choroidal neovascularization in the mouse retina.
Journal ArticleDOI

Cas-Database: web-based genome-wide guide RNA library design for gene knockout screens using CRISPR-Cas9

TL;DR: An online tool, Cas-Database, a genome-wide gRNA library design tool for Cas9 nucleases from Streptococcus pyogenes (SpCas9) with an easy-to-use web interface, which provides a powerful way to select multiple optimal target sequences from thousands of genes at once for the creation of a genomes-wide library.
Journal ArticleDOI

Fusion guide RNAs for orthogonal gene manipulation with Cas9 and Cpf1.

TL;DR: A fusion guide RNA that functions with both Cas9 and Cpf1 proteins to induce mutations in human cells is developed and it is demonstrated that fgRNAs can be used in multiplex genome editing and orthogonal genome manipulation with two types of Cas proteins.