J
Jin-Soo Kim
Researcher at Seoul National University
Publications - 308
Citations - 26566
Jin-Soo Kim is an academic researcher from Seoul National University. The author has contributed to research in topics: CRISPR & Genome editing. The author has an hindex of 66, co-authored 264 publications receiving 21375 citations. Previous affiliations of Jin-Soo Kim include UPRRP College of Natural Sciences & Korea University of Science and Technology.
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Journal ArticleDOI
ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update.
Robin Lovell-Badge,Eric Anthony,Roger A. Barker,Tania Bubela,Ali H. Brivanlou,Melissa K. Carpenter,R. Alta Charo,Amander T. Clark,Ellen Wright Clayton,Yali Cong,George Q. Daley,Jianping Fu,Misao Fujita,Andy Greenfield,Steve A. Goldman,Steve A. Goldman,Lori R. Hill,Insoo Hyun,Insoo Hyun,Rosario Isasi,Jeffrey P. Kahn,Kazuto Kato,Jin-Soo Kim,Jonathan Kimmelman,Jürgen A. Knoblich,Debra J. H. Mathews,Nuria Montserrat,Jack Mosher,Megan Munsie,Hiromitsu Nakauchi,Hiromitsu Nakauchi,Luigi Naldini,Gail Naughton,Kathy K. Niakan,Kathy K. Niakan,Ubaka Ogbogu,Roger A. Pedersen,Nicolas C. Rivron,Heather M. Rooke,Janet Rossant,Jeff Round,Mitinori Saitou,Douglas Sipp,Julie Steffann,Jeremy Sugarman,Azim Surani,Jun Takahashi,Fuchou Tang,Leigh Turner,Patricia J. Zettler,Xiaomei Zhai +50 more
TL;DR: The International Society for Stem Cell Research (ISCR) as discussed by the authors updated its guidelines for stem cell research and clinical translation in order to address advances in stem cell science and other relevant fields, together with the associated ethical, social, and policy issues that have arisen since the last update in 2016.
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Structural roles of guide RNAs in the nuclease activity of Cas9 endonuclease.
Youngbin Lim,So Young Bak,Keewon Sung,Euihwan Jeong,Seung-Hwan Lee,Jin-Soo Kim,Sangsu Bae,Sangsu Bae,Seong Keun Kim +8 more
TL;DR: It is concluded that both tracrRNA and crRNA regulate the conformations and kinetics of the Cas9 complex, which are crucial in the DNA cleavage activity of the CRISPR-Cas9 system.
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Preassembled zinc-finger arrays for rapid construction of ZFNs
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Adenine base editors catalyze cytosine conversions in human cells
TL;DR: Adenine base editor–induced cytosine substitutions occur independently of adenosine conversions with an efficiency of up to 11.2% and reduce the number of suitable targeting sites for high-specificity base editing.
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Genome editing comes of age
TL;DR: This work highlights the key advances that set the foundation for the rapid and widespread implementation of CRISPR–Cas9 genome editing approaches that has revolutionized the field.