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Jing Tu

Researcher at Leiden University

Publications -  15
Citations -  548

Jing Tu is an academic researcher from Leiden University. The author has contributed to research in topics: Mesoporous silica & Lipid bilayer. The author has an hindex of 10, co-authored 13 publications receiving 454 citations. Previous affiliations of Jing Tu include Xiamen University.

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Multifunctional ZnPc-loaded mesoporous silica nanoparticles for enhancement of photodynamic therapy efficacy by endolysosomal escape.

TL;DR: A strategy for enhancement of PDT efficacy by endolysosomal escape is presented and the promise of using multifunctional MSNs for cancer therapy is highlighted.
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Mesoporous Silica Nanoparticles with Large Pores for the Encapsulation and Release of Proteins

TL;DR: These MSNs with their large surface area and optimal dimensions provide a scaffold with a high encapsulation efficiency and controllable release profiles for a variety of proteins, enabling potential applications in fields such as drug delivery and protein therapy.
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Intradermal vaccination with hollow microneedles: A comparative study of various protein antigen and adjuvant encapsulated nanoparticles.

TL;DR: The applicator controlled hollow microneedle delivery is an excellent method for intradermal injection of nanoparticle vaccines, allowing selection of optimal nanoparticle formulations for humoral and cellular immune responses.
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Membrane Fusion Mediated Intracellular Delivery of Lipid Bilayer Coated Mesoporous Silica Nanoparticles.

TL;DR: C cuboidal mesoporous silica nanoparticles containing disk‐shaped cavities with a large pore diameter (10 nm) are studied as a protein delivery vehicle using cytochrome‐c (cytC) as a model membrane‐impermeable protein to suggest a universal way for the efficient delivery of any type of inorganic nanoparticle or protein into cells mediated by CC induced membrane fusion.
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Mesoporous Silica Nanoparticle-Coated Microneedle Arrays for Intradermal Antigen Delivery.

TL;DR: Microneedle arrays coated with LB-MSN-OVA were successfully developed and shown to be suitable for intradermal delivery of the encapsulated protein antigen.