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João P. André

Researcher at University of Minho

Publications -  46
Citations -  1259

João P. André is an academic researcher from University of Minho. The author has contributed to research in topics: DOTA & Nuclear magnetic resonance spectroscopy. The author has an hindex of 16, co-authored 43 publications receiving 1163 citations. Previous affiliations of João P. André include University Hospital of Basel.

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68Ga-PET: a powerful generator-based alternative to cyclotron-based PET radiopharmaceuticals

TL;DR: In this paper, a variety of mono-and bifunctional chelators have been developed which allow the formation of stable (68)Ga(3+)complexes and convenient coupling to biomolecules.
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High Relaxivity for Monomeric Gd(DOTA)‐Based MRI Contrast Agents, Thanks to Micellar Self‐Organization

TL;DR: A new amphiphilic GdIIIchelate, which is capable of forming micelles in aqueous solution, has been synthesized and has high proton relaxivities that thus far have only been obtained with macromolecular complexes.
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Lanthanide(III) complexes of DOTA-glycoconjugates: a potential new class of lectin-mediated medical imaging agents.

TL;DR: The synthesis and characterization of a new class of DOTA monoamide-linked glycoconjugates of different valencies and their Sm(III), Eu( III) and Gd(III) complexes are reported, yielding parameters close to those reported for other DOTA Monoamides.
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1,4,7-Triazacyclononane-1-succinic acid-4,7-diacetic acid (NODASA): a new bifunctional chelator for radio gallium-labelling of biomolecules

TL;DR: A new bifunctional chelator NODASA (1,4,7-triazacyclononane-1-succinic acid-4, 7-diacetic acid) has been synthesised and its kinetically inert gallium(III) complex was crystallographically characterized and conjugated to a model aminoacidamide showing the feasibility of a prelabelling approach with 68,67Ga.
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Alkaline Earth Metal and Lanthanide(III) Complexes of Ligands Based upon 1,4,7,10-Tetraazacyclododecane-1,7-bis(acetic acid).

TL;DR: The macrocyclic ligand DO2A (1,4,7,10-tetraazacyclodododecane-1,7-bis(acetic acid) was prepared and used as a building block for four new macro cyclic ligands having mixed side-chain chelating groups and was found to be more stable than the corresponding Mg(II) complexes.