João Pedroso Lima

TL;DR: The synthesis and characterization of a new class of DOTA monoamide-linked glycoconjugates of different valencies and their Sm(III), Eu( III) and Gd(III) complexes are reported, yielding parameters close to those reported for other DOTA Monoamides.

TL;DR: Nuclear medicine (NM) studies in vivo are used to detect minimal amounts of radiopharmaceuticals in organs and their course over time, resulting from physico-chemical interactions of the tracers within the body, in the sequence of specific physiological processes.

TL;DR: In vitro experiments demonstrated that GdDOTP5−-induced changes in relaxivity were silenced upon HA binding but could be recovered by acid elution of the complex, suggesting a novel strategy for creating highly sensitive, switchable MRI contrast agents.

TL;DR: The proposed method enables visualization of deep lymphatic lung network and lymph nodes and this technique involving the modulation of nanoradioliposomes targeting specific organs or tissues may be an important tool for diagnostic or even for therapeutic purposes.

TL;DR: In this article, the performance of spark chambers is described and discussed, which are designed to visualise the distribution of β-emitting radioactivity on chromatograms, and they lead to ease of construction with good uniformity of sensitivity and stability of operation.