J
John A. Zaia
Researcher at City of Hope National Medical Center
Publications - 209
Citations - 11560
John A. Zaia is an academic researcher from City of Hope National Medical Center. The author has contributed to research in topics: Transplantation & Human cytomegalovirus. The author has an hindex of 53, co-authored 198 publications receiving 11145 citations. Previous affiliations of John A. Zaia include Massachusetts Department of Public Health & Harvard University.
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Journal ArticleDOI
Ribozymes as potential anti-HIV-1 therapeutic agents.
Nava Sarver,Edouard M. Cantin,Pairoj Chang,Pairoj Chang,John A. Zaia,Paula A. Ladne,Delilah A. Stephens,John J. Rossi +7 more
TL;DR: The present study shows precise cleavage of human immunodeficiency virus type 1 (HIV-1) sequences in a cell-free system by hammerhead ribozymes, suggesting the feasibility of developing Ribozymes as therapeutic agents against human pathogens such as HIV-1.
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A randomized, controlled trial of prophylactic ganciclovir for cytomegalovirus pulmonary infection in recipients of allogeneic bone marrow transplants; The City of Hope-Stanford-Syntex CMV Study Group.
TL;DR: A controlled trial of ganciclovir in recipients of bone marrow transplants who had asymptomatic pulmonary CMV infection and sought to identify risk factors for the development of CMV interstitial pneumonia.
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Towards an HIV cure: a global scientific strategy
Steven G. Deeks,Brigitte Autran,Ben Berkhout,Monsef Benkirane,Scott Cairns,Nicolas Chomont,Tae Wook Chun,Melissa J Churchill,Michele Di Mascio,Christine Katlama,Alain Lafeuillade,Alan L. Landay,Michael M. Lederman,Sharon R Lewin,Frank Maldarelli,David M. Margolis,Martin Markowitz,Javier Martinez-Picado,James I. Mullins,John W. Mellors,Santiago Moreno,Una O'Doherty,Sarah Palmer,Marie Capucine Penicaud,Matija Peterlin,Guido Poli,Jean-Pierre Routy,Christine Rouzioux,Guido Silvestri,Mario Stevenson,Amalio Telenti,Carine Van Lint,Eric Verdin,Anne Woolfrey,John A. Zaia,Françoise Barré-Sinoussi +35 more
TL;DR: The International AIDS Society convened a group of international experts to develop a scientific strategy for research towards an HIV cure and several priorities for basic, translational and clinical research were identified.
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Cytomegalovirus in hematopoietic stem cell transplant recipients: Current status, known challenges, and future strategies.
Michael Boeckh,W. Garrett Nichols,Genovefa A. Papanicolaou,Robert H. Rubin,John R. Wingard,John A. Zaia +5 more
TL;DR: Primary CMV infection via blood transfusion can be reduced by the provision of seronegative or leukocyte-depleted blood products, and indirect immunomodulatory effects of CMV are increasingly recognized in hematopoietic stem cell transplant recipients.
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Identification of the major late human cytomegalovirus matrix protein pp65 as a target antigen for CD8+ virus-specific cytotoxic T lymphocytes
Elizabeth McLaughlin-Taylor,Hema Pande,Stephen J. Forman,Becky Tanamachi,Cheng Rong Li,John A. Zaia,Philip D. Greenberg,Stanley R. Riddell +7 more
TL;DR: The observation that CMV‐specific CTL can be induced in vitro using peptide fragments derived from pp65 supports the future use and manipulation of this and similar effector populations in a clinical setting.