J
John B. Dame
Researcher at University of Florida
Publications - 91
Citations - 4897
John B. Dame is an academic researcher from University of Florida. The author has contributed to research in topics: Plasmepsin & Plasmodium falciparum. The author has an hindex of 42, co-authored 91 publications receiving 4744 citations. Previous affiliations of John B. Dame include Washington State University & Ross University School of Veterinary Medicine.
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Journal ArticleDOI
Host Movement and the Genetic Structure of Populations of Parasitic Nematodes
TL;DR: It appears that host movement is an important determinant of population genetic structure in these nematodes, and large effective population sizes appear to be the most likely explanation for high within-population diversities.
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The Plasmodium falciparum translationally controlled tumor protein homolog and its reaction with the antimalarial drug artemisinin.
Jamaree Bhisutthibhan,Xing-Qing Pan,Paul A. Hossler,Daniel J. Walker,Charles A. Yowell,Jane M. Carlton,John B. Dame,Steven R. Meshnick +7 more
TL;DR: TCTP reacts with artemisinin in situ and in vitro in the presence of hemin and appears to bind to hemin.
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Substitution bias, rapid saturation, and the use of mtDNA for nematode systematics.
TL;DR: The usefulness of mtDNA for nematode phylogeny reconstruction is examined and data that can be used for a priori character weighting or for parameter specification in models of sequence evolution is provided.
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Co-ordinated programme of gene expression during asexual intraerythrocytic development of the human malaria parasite Plasmodium falciparum revealed by microarray analysis.
Choukri Ben Mamoun,Ilya Y. Gluzman,Ilya Y. Gluzman,Christian T. Hott,Sandra MacMillan,Aloka S. Amarakone,Dustin L. Anderson,Jane M. Carlton,John B. Dame,Debopam Chakrabarti,Rodger K. Martin,Bernard H. Brownstein,Daniel E. Goldberg,Daniel E. Goldberg +13 more
TL;DR: Developmental upregulation of specific mRNAs was found to cluster into functional groups and revealed a co‐ordinated programme of gene expression, which will facilitate functional analysis of the P. falciparum genome and identify genes with a critical role in parasite progression and multiplication in the human host.
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The shikimate pathway and its branches in apicomplexan parasites.
Craig W. Roberts,Fiona Roberts,Russell E. Lyons,Michael J. Kirisits,Ernest Mui,John R. Finnerty,Jennifer J. Johnson,David J. P. Ferguson,John R. Coggins,Tino Krell,Graham H. Coombs,Wilbur K. Milhous,Dennis E. Kyle,Saul Tzipori,John Barnwell,John B. Dame,Jane M. Carlton,Rima McLeod +17 more
TL;DR: These findings emphasize the potential benefits of developing additional effective inhibitors of the shikimate pathway that may function as broad-spectrum antimicrobial agents that are effective against bacterial and fungal pathogens and apicomplexan parasites.