J
John E. Greenlee
Researcher at University of Utah
Publications - 95
Citations - 2740
John E. Greenlee is an academic researcher from University of Utah. The author has contributed to research in topics: Antigen & Paraneoplastic cerebellar degeneration. The author has an hindex of 30, co-authored 84 publications receiving 2459 citations. Previous affiliations of John E. Greenlee include Veterans Health Administration & United States Department of Veterans Affairs.
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Journal ArticleDOI
Antibodies to cerebellar Purkinje cells in patients with paraneoplastic cerebellar degeneration and ovarian carcinoma.
John E. Greenlee,H R Brashear +1 more
TL;DR: The present study documents the presence of antibodies to Purkinje cells in patients with ovarian carcinoma and cerebellar degeneration and demonstrates that development of these antibodies may antedate the onset of clinically evident cerebellary degeneration.
Journal ArticleDOI
Recommended diagnostic criteria for paraneoplastic neurological syndromes
TL;DR: An important finding over recent years has been that many affected patients have serum and cerebrospinal fluid antibodies that are reactive with internal neuronal antigens, and tumours from someaffected patients have been found to express proteins that express proteins from the immune system.
Journal ArticleDOI
Chronic Meningitis Investigated via Metagenomic Next-Generation Sequencing.
Michael R. Wilson,Brian D. O’Donovan,Jeffrey M. Gelfand,Hannah A. Sample,Felicia C. Chow,John P. Betjemann,Maulik P. Shah,Megan B. Richie,Mark P. Gorman,Rula A. Hajj-Ali,Leonard H. Calabrese,Kelsey C. Zorn,Eric D. Chow,John E. Greenlee,John E. Greenlee,Jonathan H Blum,Gary Green,Lillian M. Khan,Debarko Banerji,Chaz Langelier,Chloe Bryson-Cahn,Whitney E. Harrington,Whitney E. Harrington,Jairam R Lingappa,Niraj M. Shanbhag,Ari J. Green,Bruce J. Brew,Bruce J. Brew,Ariane Soldatos,Luke Strnad,Sarah B Doernberg,Cheryl A. Jay,Vanja C. Douglas,S. Andrew Josephson,Joseph L. DeRisi +34 more
TL;DR: Diverse microbial pathogens were identified by mNGS in the CSF of patients with diagnostically challenging subacute or chronic meningitis, including a case of subarachnoid neurocysticercosis that defied diagnosis for 1 year, and the first reported case of CNS vasculitis caused by Aspergillus oryzae.
Journal ArticleDOI
Type iia ('anti-hu') antineuronal antibodies produce destruction of rat cerebellar granule neurons in vitro
TL;DR: The present study provides the first reported evidence that type IIa antibodies may cause cell injury directly, in the absence of lymphocyte-mediated immune response.
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Guidelines on the detection of paraneoplastic anti-neuronal-specific antibodies: Report from the Workshop to the Fourth Meeting of the International Society of Neuro-Immunology on paraneoplastic neurological disease, held October 22-23, 1994, in Rotterdam, The Netherlands
J.W.B. Moll,J. C. Antoine,H. R. Brashear,J.Y. Delattre,M. Drlicek,Edward J. Dropcho,B. Giometto,Francesc Graus,John E. Greenlee,J. Honnorat,Kurt A. Jaeckle,K. Tanaka,Charles J. Vecht +12 more
TL;DR: A clinical diagnosis of PNS is supported by the finding of these specific anti-neuronal antibodies and the detection of these antibodies should also lead to a focused search for specific underlying neoplasms.