J
John F. Ensley
Researcher at Wayne State University
Publications - 123
Citations - 16987
John F. Ensley is an academic researcher from Wayne State University. The author has contributed to research in topics: Epidermoid carcinoma & Head and neck squamous-cell carcinoma. The author has an hindex of 45, co-authored 123 publications receiving 15911 citations. Previous affiliations of John F. Ensley include University of Michigan & Johns Hopkins University.
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Concurrent chemotherapy and radiotherapy for organ preservation in advanced laryngeal cancer
Arlene A. Forastiere,Helmuth Goepfert,Moshe H. Maor,Thomas F. Pajak,Randal S. Weber,William H. Morrison,Bonnie S. Glisson,Andy Trotti,John A. Ridge,C. Chao,Glen Peters,Ding Jen Lee,Andrea Leaf,John F. Ensley,Jay S. Cooper +14 more
TL;DR: In patients with laryngeal cancer, radiotherapy with concurrent administration of cisplatin is superior to induction chemotherapy followed by radiotherapy or radiotherapy alone for larynGEal preservation and locoregional control.
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Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck.
Jay S. Cooper,Thomas F. Pajak,Arlene A. Forastiere,John R. Jacobs,Bruce H. Campbell,Scott Saxman,Julie A. Kish,Harold Kim,Anthony J. Cmelak,Marvin Rotman,Mitchell Machtay,John F. Ensley,K.S.Clifford Chao,Christopher J. Schultz,Nancy M. Lee,Karen K. Fu +15 more
TL;DR: Among high-risk patients with resected head and neck cancer, concurrent postoperative chemotherapy and radiotherapy significantly improve the rates of local and regional control and disease-free survival, however, the combined treatment is associated with a substantial increase in adverse effects.
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Chemoradiotherapy versus radiotherapy in patients with advanced nasopharyngeal cancer: phase III randomized Intergroup study 0099.
Muhyi Al-Sarraf,Michael LeBlanc,P.G. Giri,Karen K. Fu,Jay S. Cooper,T. Vuong,Arlene A. Forastiere,George L. Adams,Wael Sakr,David E. Schuller,John F. Ensley +10 more
TL;DR: It is concluded that chemoradiotherapy is superior to radiotherapy alone for patients with advanced nasopharyngeal cancers with respect to PFS and overall survival.
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An Intergroup Phase III Comparison of Standard Radiation Therapy and Two Schedules of Concurrent Chemoradiotherapy in Patients With Unresectable Squamous Cell Head and Neck Cancer
David J. Adelstein,Yi Li,George L. Adams,Henry N. Wagner,Julie A. Kish,John F. Ensley,David E. Schuller,Arlene A. Forastiere +7 more
TL;DR: The addition of concurrent high-dose, single-agent cisplatin to conventional single daily fractionated radiation significantly improves survival, although it also increases toxicity.
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Long-Term Results of RTOG 91-11: A Comparison of Three Nonsurgical Treatment Strategies to Preserve the Larynx in Patients With Locally Advanced Larynx Cancer
Arlene A. Forastiere,Qiang Zhang,Randal S. Weber,Moshe H. Maor,Helmuth Goepfert,Thomas F. Pajak,William H. Morrison,Bonnie S. Glisson,Andy Trotti,John A. Ridge,Wade L. Thorstad,Henry N. Wagner,John F. Ensley,Jay S. Cooper +13 more
TL;DR: These 10-year results show that induction PF followed by RT and concomitant cisplatin/RT show similar efficacy for the composite end point of LFS, and new strategies that improve organ preservation and function with less morbidity are needed.