Q
Qiang Zhang
Researcher at Radiation Therapy Oncology Group
Publications - 39
Citations - 4402
Qiang Zhang is an academic researcher from Radiation Therapy Oncology Group. The author has contributed to research in topics: Chemoradiotherapy & Radiation therapy. The author has an hindex of 19, co-authored 35 publications receiving 3726 citations. Previous affiliations of Qiang Zhang include American College of Radiology & Aarhus University Hospital.
Papers
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Journal ArticleDOI
Long-Term Results of RTOG 91-11: A Comparison of Three Nonsurgical Treatment Strategies to Preserve the Larynx in Patients With Locally Advanced Larynx Cancer
Arlene A. Forastiere,Qiang Zhang,Randal S. Weber,Moshe H. Maor,Helmuth Goepfert,Thomas F. Pajak,William H. Morrison,Bonnie S. Glisson,Andy Trotti,John A. Ridge,Wade L. Thorstad,Henry N. Wagner,John F. Ensley,Jay S. Cooper +13 more
TL;DR: These 10-year results show that induction PF followed by RT and concomitant cisplatin/RT show similar efficacy for the composite end point of LFS, and new strategies that improve organ preservation and function with less morbidity are needed.
Journal ArticleDOI
Tobacco Smoking and Increased Risk of Death and Progression for Patients With p16-Positive and p16-Negative Oropharyngeal Cancer
Maura L. Gillison,Qiang Zhang,Richard C.K. Jordan,Weihong Xiao,William H. Westra,Andy Trotti,Sharon A. Spencer,Jonathan Harris,Christine H. Chung,K. Kian Ang +9 more
TL;DR: Risk of oropharyngeal cancer progression and death increases directly as a function of tobacco exposure at diagnosis and during therapy and is independent of tumor p16 status and treatment.
Journal ArticleDOI
Human Papillomavirus and Overall Survival After Progression of Oropharyngeal Squamous Cell Carcinoma
Carole Fakhry,Qiang Zhang,Phuc Felix Nguyen-Tan,David I. Rosenthal,Adel K. El-Naggar,Adam S. Garden,Denis Soulières,Andy Trotti,Vilija N. Avizonis,John A. Ridge,Jonathan Harris,Quynh-Thu Le,Maura L. Gillison +12 more
TL;DR: Tumor HPV status is a strong and independent predictor of OS after disease progression and should be a stratification factor for clinical trials for patients with recurrent or metastatic OPC.
Journal ArticleDOI
Long-term follow-up of the RTOG 9501/intergroup phase III trial: postoperative concurrent radiation therapy and chemotherapy in high-risk squamous cell carcinoma of the head and neck.
Jay S. Cooper,Qiang Zhang,Thomas F. Pajak,Arlene A. Forastiere,John R. Jacobs,Scott Saxman,Julie A. Kish,Harold Kim,Anthony J. Cmelak,Marvin Rotman,Robert H. Lustig,John F. Ensley,Wade L. Thorstad,Christopher J. Schultz,Sue S. Yom,K. Kian Ang +15 more
TL;DR: Analysis of the subgroup of patients who had either microscopically involved resection margins and/or extracapsular spread of disease showed improved local-regional control and disease-free survival with concurrent administration of chemotherapy, and no significant differences in outcome were observed in the analysis of all randomized eligible patients.
Journal ArticleDOI
p16 Protein Expression and Human Papillomavirus Status As Prognostic Biomarkers of Nonoropharyngeal Head and Neck Squamous Cell Carcinoma
Christine H. Chung,Qiang Zhang,Christina S. Kong,Jonathan Harris,Elana J. Fertig,Paul M. Harari,Dian Wang,Kevin P. Redmond,George Shenouda,Andy Trotti,David Raben,Maura L. Gillison,Richard C.K. Jordan,Quynh-Thu Le +13 more
TL;DR: Patients with p 16-negative non-OPSCC have worse outcomes than patients with p16-positive non-opsCC, and HPV may also have a role in outcome in a subset of non-OPSC, however, further development of a p16 IHC scoring system in non- OPSCC and improvement of HPV detection methods are warranted.