R
Randal S. Weber
Researcher at University of Texas MD Anderson Cancer Center
Publications - 431
Citations - 34920
Randal S. Weber is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Cancer & Head and neck cancer. The author has an hindex of 80, co-authored 421 publications receiving 30453 citations. Previous affiliations of Randal S. Weber include University of Texas at Austin & Johns Hopkins University.
Papers
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Journal ArticleDOI
Human Papillomavirus and Survival of Patients with Oropharyngeal Cancer
K. Kian Ang,Jonathan Harris,Richard H. Wheeler,Randal S. Weber,David I. Rosenthal,Phuc Felix Nguyen-Tân,William H. Westra,Christine H. Chung,Richard C.K. Jordan,Charles Lu,Harold Kim,Rita Axelrod,C Craig Silverman,Kevin P. Redmond,Maura L. Gillison +14 more
TL;DR: Tumor HPV status is a strong and independent prognostic factor for survival among patients with oropharyngeal cancer and the risk of death significantly increased with each additional pack-year of tobacco smoking.
Journal ArticleDOI
Concurrent chemotherapy and radiotherapy for organ preservation in advanced laryngeal cancer
Arlene A. Forastiere,Helmuth Goepfert,Moshe H. Maor,Thomas F. Pajak,Randal S. Weber,William H. Morrison,Bonnie S. Glisson,Andy Trotti,John A. Ridge,C. Chao,Glen Peters,Ding Jen Lee,Andrea Leaf,John F. Ensley,Jay S. Cooper +14 more
TL;DR: In patients with laryngeal cancer, radiotherapy with concurrent administration of cisplatin is superior to induction chemotherapy followed by radiotherapy or radiotherapy alone for larynGEal preservation and locoregional control.
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Factors Associated With Severe Late Toxicity After Concurrent Chemoradiation for Locally Advanced Head and Neck Cancer: An RTOG Analysis
Mitchell Machtay,Jennifer Moughan,Andrew Trotti,Adam S. Garden,Randal S. Weber,Jay S. Cooper,Arlene A. Forastiere,K. Kian Ang +7 more
TL;DR: Older age, advanced T-stage, and larynx/hypopharynx primary site were strong independent risk factors and neck dissection after CCRT was associated with an increased risk of these complications.
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Long-Term Results of RTOG 91-11: A Comparison of Three Nonsurgical Treatment Strategies to Preserve the Larynx in Patients With Locally Advanced Larynx Cancer
Arlene A. Forastiere,Qiang Zhang,Randal S. Weber,Moshe H. Maor,Helmuth Goepfert,Thomas F. Pajak,William H. Morrison,Bonnie S. Glisson,Andy Trotti,John A. Ridge,Wade L. Thorstad,Henry N. Wagner,John F. Ensley,Jay S. Cooper +13 more
TL;DR: These 10-year results show that induction PF followed by RT and concomitant cisplatin/RT show similar efficacy for the composite end point of LFS, and new strategies that improve organ preservation and function with less morbidity are needed.
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Randomized Phase III Trial of Concurrent Accelerated Radiation Plus Cisplatin With or Without Cetuximab for Stage III to IV Head and Neck Carcinoma: RTOG 0522
K. Kian Ang,Qiang Zhang,David I. Rosenthal,Phuc Felix Nguyen-Tan,Eric J. Sherman,Randal S. Weber,James M. Galvin,James A. Bonner,Jonathan Harris,Adel K. El-Naggar,Maura L. Gillison,Richard C.K. Jordan,Andre Konski,Wade L. Thorstad,Andy Trotti,Jonathan J. Beitler,Adam S. Garden,William J. Spanos,Sue S. Yom,Rita Axelrod +19 more
TL;DR: Adding cetuximab to radiation-cisplatin did not improve outcome and hence should not be prescribed routinely, and the PFS and OS were higher in patients with p16-positive OPC, but outcomes did not differ by EGFR expression.