John J. P. Brevé

TL;DR: In vivo homing studies revealed that these modified vessels support minimal lymphocyte traffic from the blood, and data reveal that functioning afferent lymphatics are centrally involved in maintaining normal lymph node homeostasis.

TL;DR: It is shown that the genetic profile of microglia already differs between different brain regions when studied under control conditions, which implies that brain region-specific microglial gene expression profiles exist that may contribute to the region- specific differences in microglian responsivity during disease conditions, such as seen in, e.g., PD.

TL;DR: The results indicate that emotional stress can rapidly induce altered behavior of AM, which is discussed in view of the important role these cells play in the regulation of the local immune responses in the lungs and the possible contribution to asthma.

TL;DR: The results indicate that not all antigen-bearing Langerhans cells migrate from the skin after application of a contact sensitizer, indicating that signals in addition to simple antigen binding are necessary for migration.

TL;DR: It was found that dendritic cells derived from the oral mucosa were not able to transfer tolerance, but that they acted as antigen-presenting cells in sensu stricto irrespective of the source and route of antigen administration.