J
John R. Gallagher
Researcher at National Institutes of Health
Publications - 28
Citations - 1774
John R. Gallagher is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Hemagglutinin (influenza) & Antibody. The author has an hindex of 13, co-authored 23 publications receiving 1436 citations. Previous affiliations of John R. Gallagher include University of Pennsylvania.
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Journal ArticleDOI
Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection
Hadi M. Yassine,Jeffrey C. Boyington,Patrick M. McTamney,Patrick M. McTamney,Chih Jen Wei,Chih Jen Wei,Masaru Kanekiyo,Wing Pui Kong,John R. Gallagher,Lingshu Wang,Yi Zhang,M. Gordon Joyce,Daniel Lingwood,Daniel Lingwood,Syed M. Moin,Hanne Andersen,Yoshinobu Okuno,Srinivas S. Rao,Srinivas S. Rao,Audray K. Harris,Peter D. Kwong,John R. Mascola,Gary J. Nabel,Gary J. Nabel,Barney S. Graham +24 more
TL;DR: Vaccination of mice and ferrets with H1–SS–np elicited broadly cross-reactive antibodies that completely protected mice and partially protected ferrets against lethal heterosubtypic H5N1 influenza virus challenge despite the absence of detectable H 5N1 neutralizing activity in vitro.
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Rapid development of a DNA vaccine for Zika virus
Kimberly A. Dowd,Sung-Youl Ko,Kaitlyn M. Morabito,Eun Sung Yang,Rebecca S. Pelc,Christina R. DeMaso,Leda R. Castilho,Leda R. Castilho,Peter Abbink,Michael R. Boyd,Ramya Nityanandam,David N. Gordon,John R. Gallagher,Xuejun Chen,John-Paul Todd,Yaroslav Tsybovsky,Audray K. Harris,Yan-Jang S. Huang,Stephen Higgs,Dana L. Vanlandingham,Hanne Andersen,Mark G. Lewis,Rafael De La Barrera,Kenneth H. Eckels,Richard G. Jarman,Martha Nason,Dan H. Barouch,Mario Roederer,Wing-Pui Kong,John R. Mascola,Theodore C. Pierson,Barney S. Graham +31 more
TL;DR: It is found that vaccination with DNA expressing the premembrane and envelope proteins of ZIKV was immunogenic in mice and nonhuman primates, and protection against viremia after ZikV challenge correlated with serum neutralizing activity.
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Herpes virus fusion and entry: a story with many characters.
Roselyn J. Eisenberg,Doina Atanasiu,Tina M. Cairns,John R. Gallagher,Claude Krummenacher,Gary H. Cohen +5 more
TL;DR: The model for how herpes simplex virus (HSV) regulates fusion in series of highly regulated steps is presented and provides a framework to address mechanistic questions about fusion by HSV and herpesviruses in general.
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Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses
Masaru Kanekiyo,M. Gordon Joyce,M. Gordon Joyce,Rebecca A. Gillespie,John R. Gallagher,Sarah F. Andrews,Hadi M. Yassine,Hadi M. Yassine,Adam K. Wheatley,Adam K. Wheatley,Brian E. Fisher,David R. Ambrozak,Adrian Creanga,Kwanyee Leung,Eun Sung Yang,Seyhan Boyoglu-Barnum,Ivelin S. Georgiev,Ivelin S. Georgiev,Yaroslav Tsybovsky,Madhu Prabhakaran,Hanne Andersen,Wing-Pui Kong,Ulrich Baxa,Kathryn L Zephir,Julie E. Ledgerwood,Richard A. Koup,Peter D. Kwong,Audray K. Harris,Adrian B. McDermott,John R. Mascola,Barney S. Graham +30 more
TL;DR: A mosaic nanoparticle vaccine against influenza virus that is able to elicit neutralizing antibodies that span nearly 100 years of variation of influenza A virus is developed.
Journal ArticleDOI
IL-21 and Probiotic Therapy Improve TH17 Frequencies, Microbial Translocation, and Microbiome in ARV-Treated, SIV-Infected Macaques
Alexandra M. Ortiz,Zachary Klase,Zachary Klase,Sarah R. DiNapoli,Ivan Vujkovic-Cvijin,Kirby Carmack,Molly R. Perkins,Nina Calantone,Carol L. Vinton,Nadeene E. Riddick,John R. Gallagher,Nichole R. Klatt,Nichole R. Klatt,Joseph M. McCune,Jacob D. Estes,Mirko Paiardini,Jason M. Brenchley +16 more
TL;DR: It is proposed that combining ARVs with therapeutics aimed at restoring intestinal stasis may significantly improve disease prognosis of ARV-treated, HIV-infected individuals.