Judith H. Aberle

TL;DR: It is shown that hrsACE2 can reduce SARS-CoV-2 load by a factor of 1000–5000 in in-vitro cell-culture experiments and engineered organoids, directly demonstrating that ACE2 can effectively neutralise Sars-Cov-2.

TL;DR: This study provides a national-scale analysis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) superspreading during the first wave of infections in Austria, a country that played a major role in initial virus transmissions in Europe.

TL;DR: In this article, SARS-CoV-2-specific T-cell responses were quantified by IFNγ enzyme-linked immunosorbent spot assays using the Elecsys Anti-SARS CoV2 S immunoassay against the receptor-binding domain (RBD) of the spike protein and neutralisation tests.

TL;DR: It was found that dual infections with non-RSV respiratory viruses induced peripheral blood mononuclear cell IFN-γ responses that mimic those of single infections, whereas coinfection with RSV was associated with reduced IFN -γ responses and a more severe clinical course of lower respiratory tract disease.

TL;DR: The results demonstrate that the ELISA is reliable for rapid laboratory diagnosis of influenza in infants and young children, but for older patients application of RT-PCR or virus isolation is necessary to avoid false negative results.