Tamara Seitz

TL;DR: It is shown that hrsACE2 can reduce SARS-CoV-2 load by a factor of 1000–5000 in in-vitro cell-culture experiments and engineered organoids, directly demonstrating that ACE2 can effectively neutralise Sars-Cov-2.

TL;DR: The TTV level may be used to mirror the state of immunosuppression only after the patients’ initial peak TTVlevel is reached, and was not associated with time and level of the patients' post-transplant TTV peak load.

TL;DR: A rapid, robust, highly sensitive and versatile RT-LAMP based SARS-CoV-2 detection assay that has substantially increased sensitivity and scalability, established a pipette-free version for home testing, and developed a version with open source enzymes that could be produced in any molecular biology setting.

TL;DR: The ISARIC prospective multinational observational study is the largest cohort of hospitalized patients with COVID-19 and as discussed by the authors evaluated relationships of age, sex, and nationality to presenting symptoms.

TL;DR: Novel insights are provided into the kinetics of antibody and CD4 T cell responses as well as viral loads that are key to understanding the role of adaptive immunity in combating the virus during acute infection and provide leads for the timing of immune therapies for COVID-19.