J
Judy Luden
Researcher at Cincinnati Children's Hospital Medical Center
Publications - 8
Citations - 508
Judy Luden is an academic researcher from Cincinnati Children's Hospital Medical Center. The author has contributed to research in topics: Randomized controlled trial & Transcranial Doppler. The author has an hindex of 4, co-authored 8 publications receiving 414 citations. Previous affiliations of Judy Luden include Georgia Regents University & Medical University of South Carolina.
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Journal ArticleDOI
Hydroxycarbamide versus chronic transfusion for maintenance of transcranial doppler flow velocities in children with sickle cell anaemia - TCD with Transfusions Changing to Hydroxyurea (TWiTCH): A multicentre, open-label, phase 3, non-inferiority trial
Russell E. Ware,Barry R. Davis,William H. Schultz,R. Clark Brown,Banu Aygun,Sharada A. Sarnaik,Isaac Odame,Beng Fuh,Alex George,William Owen,Lori Luchtman-Jones,Zora R. Rogers,Lee Hilliard,Cynthia Gauger,Connie M. Piccone,Margaret T. Lee,Janet L. Kwiatkowski,Sherron M. Jackson,Scott T. Miller,Carla W. Roberts,Matthew M. Heeney,Theodosia A. Kalfa,Stephen C. Nelson,Hamayun Imran,Kerri Nottage,Ofelia A. Alvarez,Melissa Rhodes,Alexis A. Thompson,Jennifer A. Rothman,Kathleen J. Helton,Donna R. Roberts,Jamie L. Coleman,Melanie J. Bonner,Abdullah Kutlar,Niren Patel,John C. Wood,Linda B. Piller,Peng Wei,Judy Luden,Nicole A. Mortier,Susan E. Stuber,Naomi L.C. Luban,Alan R. Cohen,Sara L. Pressel,Robert J. Adams +44 more
TL;DR: High-risk children with sickle cell anaemia and abnormal TCD velocities who have received at least 1 year of transfusions, and have no MRA-defined severe vasculopathy, hydroxycarbamide treatment can substitute for chronic transfusions to maintain TCD velocity and help to prevent primary stroke.
Journal ArticleDOI
Comparison of transcranial color Doppler imaging (TCDI) and transcranial Doppler (TCD) in children with sickle-cell anemia
Anne Jones,Joanna J. Seibert,Fenwick T. Nichols,David L. Kinder,Katie Cox,Judy Luden,Elizabeth Carl,Donald Brambilla,Suzanne Saccente,Robert J. Adams +9 more
TL;DR: Moves to correlate transcranial arterial time-averaged mean velocities obtained from an Acuson Transcranial Doppler Imaging to those obtained using the TCD as the gold standard for treatment decisions based on STOP were compared.
Journal ArticleDOI
Transcranial doppler ultrasonography (TCD) in infants with sickle cell anemia: Baseline data from the BABY HUG trial
Steven G. Pavlakis,Renee C. Rees,Xiangke Huang,R. Clark Brown,James F. Casella,Rathi V. Iyer,Ram Kalpatthi,Judy Luden,Scott T. Miller,Zora R. Rogers,Courtney D. Thornburg,Winfred C. Wang,Robert J. Adams +12 more
TL;DR: Transcranial Doppler ultrasonography is used to predict stroke risk in children with sickle cell anemia (SCA), but has not been adequately studied in children under age 2 years.
Journal ArticleDOI
TCD with Transfusions Changing to Hydroxyurea (TWiTCH): Hydroxyurea Therapy As an Alternative to Transfusions for Primary Stroke Prevention in Children with Sickle Cell Anemia
Russell E. Ware,Barry R. Davis,William H. Schultz,Clark Brown,Banu Aygun,Sharada A. Sarnaik,Isaac Odame,Beng Fuh,Alex George,William Owen,Lori Luchtman-Jones,Zora R. Rogers,Lee Hilliard,Cynthia Gauger,Connie M. Piccone,Margaret T. Lee,Janet L. Kwiatkowski,Sherron M. Jackson,Scott T. Miller,Carla W. Roberts,Matthew M. Heeney,Theodosia A. Kalfa,Stephen C. Nelson,Hamayun Imran,Kerri Nottage,Ofelia A. Alvarez,Melissa Rhodes,Alexis A. Thompson,Jennifer A. Rothman,Kathleen J. Helton,Donna R. Roberts,Jamie L. Coleman,Melanie J. Bonner,Abdullah Kutlar,Niren Patel,John C. Wood,Linda B. Piller,Peng Wei,Judy Luden,Nicole A. Mortier,Susan E. Stuber,Naomi L.C. Luban,Alan R. Cohen,Sara L. Pressel,Robert J. Adams +44 more
TL;DR: Iron overload improved more in the hydroxyurea arm than in the transfusion arm, with a greater average change in serum ferritin, compared to -38 ng/mL, p.
Journal ArticleDOI
TCD in Infants: A Report from the BABY HUG Trial.
Robert J. Adams,Julio C. Barredo,Duane Bonds,Clark Brown,James F. Casella,Li Daner,A. Russell Gerber,Rathi V. Iyer,Judy Luden,Scott T. Miller,Caterina P. Minniti,Sohail Rana,Renee C. Rees,Zora R. Rogers,Stuart Toledano,Winfred C. Wang,Russell E. Ware,Sherri A. Zimmerman +17 more
TL;DR: These studies provide valuable normative data for infants withSCA, and for further assessment of the effect of HU on TCD in infants with SCA as the study progresses.