J
Julia Forato
Researcher at State University of Campinas
Publications - 19
Citations - 741
Julia Forato is an academic researcher from State University of Campinas. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 6, co-authored 12 publications receiving 422 citations. Previous affiliations of Julia Forato include Imperial College London.
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Journal ArticleDOI
Evolution and epidemic spread of SARS-CoV-2 in Brazil.
Darlan da Silva Candido,Darlan da Silva Candido,Ingra Morales Claro,Jaqueline Goes de Jesus,William Marciel de Souza,Filipe R. R. Moreira,Simon Dellicour,Simon Dellicour,Thomas A. Mellan,Louis du Plessis,Rafael Henrique Moraes Pereira,Flavia C. S. Sales,Erika R. Manuli,Julien Thézé,Luiz Carlos de Almeida,Mariane Talon de Menezes,Carolina M. Voloch,Marcílio Jorge Fumagalli,Thais M. Coletti,Camila A. M. Silva,Mariana S. Ramundo,Mariene R. Amorim,Henrique Hoeltgebaum,Swapnil Mishra,Mandev S. Gill,Luiz Max Carvalho,Lewis F Buss,Carlos A. Prete,Jordan Ashworth,Helder I. Nakaya,Pedro S. Peixoto,Oliver J. Brady,Samuel M. Nicholls,Amilcar Tanuri,Átila Duque Rossi,Carlos Kaue Vieira Braga,Alexandra L. Gerber,Ana Paula de C Guimarães,Nelson Gaburo,Cecila Salete Alencar,Alessandro C. S. Ferreira,Cristiano Xavier Lima,José Eduardo Levi,Celso Francisco Hernandes Granato,Giulia M. Ferreira,Ronaldo da Silva Francisco,Fabiana Granja,Fabiana Granja,Márcia Teixeira Garcia,Maria Luiza Moretti,Mauricio W. Perroud,Terezinha M. P. P. Castineiras,Carolina S. Lazari,Sarah C. Hill,Sarah C. Hill,Andreza Aruska de Souza Santos,Camila L. Simeoni,Julia Forato,Andrei C. Sposito,Angelica Zaninelli Schreiber,Magnun N. N. Santos,Camila Zolini de Sá,Renan P. Souza,Luciana C. Resende-Moreira,Mauro M. Teixeira,Josy Hubner,Patricia Asfora Falabella Leme,Rennan G. Moreira,Maurício Lacerda Nogueira,Neil M. Ferguson,Silvia Figueiredo Costa,José Luiz Proença-Módena,Ana Tereza Ribeiro de Vasconcelos,Samir Bhatt,Philippe Lemey,Chieh-Hsi Wu,Andrew Rambaut,Nicholas J. Loman,Renato Santana Aguiar,Oliver G. Pybus,Ester Cerdeira Sabino,Ester Cerdeira Sabino,Ester Cerdeira Sabino,Nuno R. Faria,Nuno R. Faria,Nuno R. Faria +85 more
TL;DR: New light is shed on the epidemic transmission and evolutionary trajectories of SARS-CoV-2 lineages in Brazil and evidence that current interventions remain insufficient to keep virus transmission under control in this country is provided.
Data from: Evolution and epidemic spread of SARS-CoV-2 in Brazil
Darlan da Silva Candido,Ingra Morales Claro,Jaqueline Goes de Jesus,William Marciel de Souza,Filipe R. R. Moreira,Simon Dellicour,Thomas A. Mellan,Louis du Plessis,Rafael Henrique Moraes Pereira,Flavia C. S. Sales,Erika R. Manuli,Julien Thézé,Luiz Carlos de Almeida,Mariane Talon de Menezes,Carolina M. Voloch,Marcílio Jorge Fumagalli,Thais M. Coletti,Camila A. M. Silva,Mariana S. Ramundo,Mariene R. Amorim,Henrique Hoeltgebaum,Swapnil Mishra,Mandev S. Gill,Luiz Max Carvalho,Lewis F Buss,Carlos A. Prete,Jordan Ashworth,Helder I. Nakaya,Pedro S. Peixoto,Oliver J. Brady,Samuel M. Nicholls,Amilcar Tanuri,Átila Duque Rossi,Carlos Kaue Vieira Braga,Alexandra L. Gerber,Ana Paula de C Guimarães,Nelson Gaburo,Cecila Salete Alencar,Alessandro C. S. Ferreira,Cristiano Xavier Lima,José Eduardo Levi,Celso Francisco Hernandes Granato,Giulia M. Ferreira,Ronaldo da Silva Francisco,Fabiana Granja,Márcia Teixeira Garcia,Maria Luiza Moretti,Mauricio W. Perroud,Terezinha M. P. P. Castineiras,Carolina S. Lazari,Sarah C. Hill,Andreza Aruska de Souza Santos,Camila L. Simeoni,Julia Forato,Andrei C. Sposito,Angelica Zaninelli Schreiber,Magnun N. N. Santos,Camila Zolini de Sá,Renan P. Souza,Luciana C. Resende-Moreira,Mauro M. Teixeira,Josy Hubner,Patricia Asfora Falabella Leme,Rennan G. Moreira,Maurício Lacerda Nogueira,Neil M. Ferguson,Silvia Figueiredo Costa,José Luiz Proença-Módena,Ana Tereza Ribeiro de Vasconcelos,Samir Bhatt,Philippe Lemey,Chieh-Hsi Wu,Andrew Rambaut,Nicholas J. Loman,Renato Santana Aguiar,Oliver G. Pybus,Ester Cerdeira Sabino,Nuno R. Faria +77 more
TL;DR: New light is shed on the epidemic transmission and evolutionary trajectories of SARS-CoV-2 lineages in Brazil, and evidence that current interventions remain insufficient to keep virus transmission under control in the country is provided.
Journal ArticleDOI
Morphological, cellular, and molecular basis of brain infection in COVID-19 patients
Fernanda Crunfli,Victor Corasolla Carregari,Flávio P. Veras,Lucas Scardua Silva,Mateus Henrique Nogueira,André Saraiva Leão Marcelo Antunes,Pedro Henrique Vendramini,Aline Gazzola Fragnani Valenca,Caroline Brandão-Teles,Giuliana S. Zuccoli,Guilherme Reis-de-Oliveira,Licia C. Silva-Costa,Verônica M. Saia-Cereda,Bradley J. Smith,Ana Campos Codo,Gabriela Fabiano de Souza,Stéfanie Primon Muraro,Pierina Lorencini Parise,Daniel A. Toledo-Teixeira,Ícaro Maia Santos de Castro,B. M. Melo,Glaucia M. Almeida,Egidi Mayara Silva Firmino,Isadora Marques Paiva,Bruna Manuella Souza Silva,Rafaela M. Guimarães,Niele D. Mendes,Raíssa L Ludwig,Gabriel Palermo Ruiz,Thiago L. Knittel,Gustavo Gastão Davanzo,Jaqueline Aline Gerhardt,Patrícia Brito Rodrigues,Julia Forato,Mariene Ribeiro Amorim,Natalia S Brunetti,M. C. Martini,Maira N. Benatti,Sabrina Setembre Batah,Li Siyuan,Rafael Batista João,ítalo Karmann Aventurato,Mariana Rabelo de Brito,Maria J. Mendes,B Da Costa,Marina K. M. Alvim,José Roberto da Silva Júnior,Lívia Liviane Damião,Iêda Maria P de Sousa,Elessandra D da Rocha,Solange Maria Gonçalves,Luiz H Lopes da Silva,Vanessa Bettini,Brunno Machado de Campos,Guilherme Ludwig,Lucas Alves Tavares,Marjorie Cornejo Pontelli,Rosa Maria Mendes Viana,Ronaldo B. Martins,André Schwambach Vieira,José C. Alves-Filho,Eurico Arruda,Guilherme G Podolsky-Gondim,Marcelo Volpon Santos,Luciano Neder,André Damasio,Stevens K. Rehen,Marco Aurélio Ramirez Vinolo,Carolina Demarchi Munhoz,Paulo Louzada-Junior,Renê Donizeti Ribeiro de Oliveira,Fernando Q. Cunha,Helder I. Nakaya,Thais Mauad,Amaro Nunes Duarte-Neto,Luiz Fernando Ferraz da Silva,Marisa Dolhnikoff,Paulo Hilário Nascimento Saldiva,Alessandro S. Farias,Fernando Cendes,Pedro M. Moraes-Vieira,Alexandre Todorovic Fabro,Adriano Sebollela,Jose Luis Proenca-Modena,Clarissa L. Yasuda,Marcelo A. Mori,Thiago M. Cunha,Daniel Martins-de-Souza +87 more
TL;DR: It is shown that astrocytes are susceptible to SARS-CoV-2 infection through a noncanonical mechanism that involves spike–NRP1 interaction and respond to the infection by remodeling energy metabolism, which in turn alters the levels of metabolites used to fuel neurons and support neurotransmitter synthesis.
Posted ContentDOI
Evolution and epidemic spread of SARS-CoV-2 in Brazil
Darlan da Silva Candido,Ingra Morales Claro,Jaqueline Goes de Jesus,William Marciel de Souza,Filipe R. R. Moreira,Simon Dellicour,Thomas A. Mellan,Louis du Plessis,Rafael Henrique Moraes Pereira,Flavia C. S. Sales,Erika R. Manuli,Julien Thézé,Luiz Carlos de Almeida,Mariane Talon de Menezes,Carolina M. Voloch,Marcílio Jorge Fumagalli,Thais M. Coletti,Camila A. M. Silva,Mariana S. Ramundo,Mariene R. Amorim,Henrique Hoeltgebaum,Swapnil Mishra,Mandev S. Gill,Luiz Max Carvalho,Lewis F Buss,Carlos A. Prete,Jordan Ashworth,Helder I. Nakaya,Pedro S. Peixoto,Oliver J. Brady,Oliver J. Brady,Samuel M. Nicholls,Amilcar Tanuri,Átila Duque Rossi,Carlos Kaue Vieira Braga,Alexandra L. Gerber,Ana Paula de C Guimarães,Nelson Gaburo,Cecila Salete Alencar,Alessandro C. S. Ferreira,Cristiano Xavier Lima,José Eduardo Levi,Celso Francisco Hernandes Granato,Giula M. Ferreira,Ronaldo da Silva Francisco,Fabiana Granja,Márcia Teixeira Garcia,Maria Luiza Moretti,Mauricio W. Perroud,Terezinha M. P. P. Castineiras,Carolina S. Lazari,Sarah C. Hill,Andreza Aruska de Souza Santos,Camila L. Simeoni,Julia Forato,Andrei C. Sposito,Angelica Zaninelli Schreiber,Magnun N. N. Santos,Camila Zolini de Sá,Renan P. Souza,Luciana C. Resende-Moreira,Mauro M. Teixeira,Josy Hubner,Patricia Asfora Falabella Leme,Rennan G. Moreira,Maurício Lacerda Nogueira,CADDE-Genomic-Network,Neil M. Ferguson,Silvia Figueiredo Costa,José Luiz Proença-Módena,Ana Tereza Ribeiro de Vasconcelos,Samir Bhatt,Philippe Lemey,Chieh-Hsi Wu,Andrew Rambaut,Nicholas J. Loman,Renato Santana Aguiar,Oliver G. Pybus,Ester Cerdeira Sabino,Nuno R. Faria,Nuno R. Faria,Nuno R. Faria +81 more
TL;DR: Light is shed on the role of large and highly connected populated centres in the rapid ignition and establishment of SARS-CoV-2, and evidence that current interventions remain insufficient to keep virus transmission under control in Brazil is provided.
Posted ContentDOI
SARS-CoV-2 infects brain astrocytes of COVID-19 patients and impairs neuronal viability
Fernanda Crunfli,Victor Corasolla Carregari,Flávio P. Veras,Pedro Henrique Vendramini,Aline Gazzola Fragnani Valenca,André Saraiva Leão Marcelo Antunes,Carolina Brandao-Teles,Giuliana S. Zuccoli,Guilherme Reis-de-Oliveira,Licia C. Silva-Costa,Verônica M. Saia-Cereda,Bradley J. Smith,Ana Campos Codo,Gabriela Fabiano de Souza,Stéfanie Primon Muraro,Pierina Lorencini Parise,Daniel A. Toledo-Teixeira,Ícaro Maia Santos de Castro,Bruno Marcel Silva de Melo,Glaucia M. Almeida,Egidi Mayara Silva Firmino,Isadora Marques Paiva,Bruna Manuella Souza Silva,Rafaela M. Guimarães,Niele D. Mendes,Raissa G. Ludwig,Gabriel Palermo Ruiz,Thiago L. Knittel,Gustavo Gastão Davanzo,Jaqueline Aline Gerhardt,Patrícia Brito Rodrigues,Julia Forato,Mariene R. Amorim,Natália Brunetti Silva,M. C. Martini,Maira N. Benatti,Sabrina Setembre Batah,Li Siyuan,Rafael Batista João,Lucas Scardua Silva,Mateus Henrique Nogueira,ítalo Karmann Aventurato,Mariana Rabelo de Brito,Marina K. M. Alvim,José Roberto da Silva Junior,Lívia Liviane Damião,Maria Ercilia de Paula Castilho Stefano,Iêda Maria Pereira de Sousa,Elessandra Dias da Rocha,Solange Maria Gonçalves,Luiz Henrique Lopes da Silva,Vanessa Bettini,Brunno Machado de Campos,Guilherme Ludwig,Lucas Alves Tavares,Marjorie Cornejo Pontelli,Rosa Maria Mendes Viana,Ronaldo B. Martins,André Schwambach Vieira,José C. Alves-Filho,Eurico de Arruda Neto,Guilherme Podolski-Gondim,Marcelo Volpon Santos,Luciano Neder,Fernando Cendes,Paulo Louzada-Junior,Renê Donizeti Ribeiro de Oliveira,Fernando Q. Cunha,André Damasio,Marco Aurélio Ramirez Vinolo,Carolina Demarchi Munhoz,Stevens K. Rehen,Helder I. Nakaya,Thais Mauad,Amaro Nunes Duarte-Neto,Luiz Fernando Ferraz da Silva,Marisa Dolhnikoff,Paulo Hilário Nascimento Saldiva,Alessandro S. Farias,Pedro M. Moraes-Vieira,Alexandre Todorovic Fabro,Adriano Sebollela,José Luiz Proença Modena,Clarissa L. Yasuda,Marcelo A. Mori,Thiago M. Cunha,Daniel Martins-de-Souza +86 more
TL;DR: The data support the model where SARS-CoV-2 reaches the brain, infects astrocytes and triggers neuropathological changes that contribute to the structural and functional alterations in the brain of COVID-19 patients.