H
Henrique Hoeltgebaum
Researcher at Imperial College London
Publications - 21
Citations - 1853
Henrique Hoeltgebaum is an academic researcher from Imperial College London. The author has contributed to research in topics: Computer science & Data stream mining. The author has an hindex of 9, co-authored 19 publications receiving 1006 citations. Previous affiliations of Henrique Hoeltgebaum include Pontifical Catholic University of Rio de Janeiro.
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Journal ArticleDOI
Genomics and epidemiology of the P.1 SARS-CoV-2 lineage in Manaus, Brazil.
Nuno R. Faria,Thomas A. Mellan,Charles Whittaker,Ingra Morales Claro,Darlan da Silva Candido,Darlan da Silva Candido,Swapnil Mishra,Myuki A E Crispim,Flavia C. S. Sales,Iwona Hawryluk,John T. McCrone,Ruben J.G. Hulswit,Lucas A M Franco,Mariana S. Ramundo,Jaqueline Goes de Jesus,Pamela S Andrade,Thais M. Coletti,Giulia M. Ferreira,Camila A. M. Silva,Erika R. Manuli,Rafael Henrique Moraes Pereira,Pedro S. Peixoto,Moritz U. G. Kraemer,Nelson Gaburo,Cecilia da C. Camilo,Henrique Hoeltgebaum,William Marciel de Souza,Esmenia C. Rocha,Leandro Marques de Souza,Mariana C. Pinho,Leonardo José Tadeu de Araújo,Frederico S V Malta,Aline B. de Lima,Joice do P. Silva,Danielle A G Zauli,Alessandro C. S. Ferreira,Ricardo P Schnekenberg,Daniel J Laydon,Patrick G T Walker,Hannah M. Schlüter,Ana L. P. dos Santos,Maria S. Vidal,Valentina S. Del Caro,Rosinaldo M. F. Filho,Helem M. dos Santos,Renato Santana Aguiar,José Luiz Proença-Módena,Bruce Walker Nelson,James A. Hay,Melodie Monod,Xenia Miscouridou,Helen Coupland,Raphael Sonabend,Michaela A. C. Vollmer,Axel Gandy,Carlos A. Prete,Vitor H. Nascimento,Marc A. Suchard,Thomas A. Bowden,Sergei L Kosakovsky Pond,Chieh-Hsi Wu,Oliver Ratmann,Neil M. Ferguson,Christopher Dye,Nicholas J. Loman,Philippe Lemey,Andrew Rambaut,Nelson Abrahim Fraiji,Maria Perpétuo Socorro Sampaio Carvalho,Oliver G. Pybus,Oliver G. Pybus,Seth Flaxman,Samir Bhatt,Samir Bhatt,Ester Cerdeira Sabino +74 more
TL;DR: In this article, the authors used a two-category dynamical model that integrates genomic and mortality data to estimate that P.1 may be 1.7-to 2.4-fold more transmissible and that previous (non-P.1) infection provides 54 to 79% of the protection against infection with P.
Journal ArticleDOI
Evolution and epidemic spread of SARS-CoV-2 in Brazil.
Darlan da Silva Candido,Darlan da Silva Candido,Ingra Morales Claro,Jaqueline Goes de Jesus,William Marciel de Souza,Filipe R. R. Moreira,Simon Dellicour,Simon Dellicour,Thomas A. Mellan,Louis du Plessis,Rafael Henrique Moraes Pereira,Flavia C. S. Sales,Erika R. Manuli,Julien Thézé,Luiz Carlos de Almeida,Mariane Talon de Menezes,Carolina M. Voloch,Marcílio Jorge Fumagalli,Thais M. Coletti,Camila A. M. Silva,Mariana S. Ramundo,Mariene R. Amorim,Henrique Hoeltgebaum,Swapnil Mishra,Mandev S. Gill,Luiz Max Carvalho,Lewis F Buss,Carlos A. Prete,Jordan Ashworth,Helder I. Nakaya,Pedro S. Peixoto,Oliver J. Brady,Samuel M. Nicholls,Amilcar Tanuri,Átila Duque Rossi,Carlos Kaue Vieira Braga,Alexandra L. Gerber,Ana Paula de C Guimarães,Nelson Gaburo,Cecila Salete Alencar,Alessandro C. S. Ferreira,Cristiano Xavier Lima,José Eduardo Levi,Celso Francisco Hernandes Granato,Giulia M. Ferreira,Ronaldo da Silva Francisco,Fabiana Granja,Fabiana Granja,Márcia Teixeira Garcia,Maria Luiza Moretti,Mauricio W. Perroud,Terezinha M. P. P. Castineiras,Carolina S. Lazari,Sarah C. Hill,Sarah C. Hill,Andreza Aruska de Souza Santos,Camila L. Simeoni,Julia Forato,Andrei C. Sposito,Angelica Zaninelli Schreiber,Magnun N. N. Santos,Camila Zolini de Sá,Renan P. Souza,Luciana C. Resende-Moreira,Mauro M. Teixeira,Josy Hubner,Patricia Asfora Falabella Leme,Rennan G. Moreira,Maurício Lacerda Nogueira,Neil M. Ferguson,Silvia Figueiredo Costa,José Luiz Proença-Módena,Ana Tereza Ribeiro de Vasconcelos,Samir Bhatt,Philippe Lemey,Chieh-Hsi Wu,Andrew Rambaut,Nicholas J. Loman,Renato Santana Aguiar,Oliver G. Pybus,Ester Cerdeira Sabino,Ester Cerdeira Sabino,Ester Cerdeira Sabino,Nuno R. Faria,Nuno R. Faria,Nuno R. Faria +85 more
TL;DR: New light is shed on the epidemic transmission and evolutionary trajectories of SARS-CoV-2 lineages in Brazil and evidence that current interventions remain insufficient to keep virus transmission under control in this country is provided.
Posted ContentDOI
Genomics and epidemiology of a novel SARS-CoV-2 lineage in Manaus, Brazil
Nuno R. Faria,Nuno R. Faria,Nuno R. Faria,Thomas A. Mellan,Charles Whittaker,Ingra Morales Claro,Darlan da Silva Candido,Darlan da Silva Candido,Swapnil Mishra,Myuki A E Crispim,Flavia C. S. Sales,Iwona Hawryluk,John T. McCrone,Ruben J.G. Hulswit,Lucas A M Franco,Mariana S. Ramundo,Jaqueline Goes de Jesus,Pamela S Andrade,Thais M. Coletti,Giulia M. Ferreira,Camila A. M. Silva,Erika R. Manuli,Rafael Henrique Moraes Pereira,Pedro S. Peixoto,Moritz U. G. Kraemer,Nelson Gaburo,Cecilia da C. Camilo,Henrique Hoeltgebaum,William Marciel de Souza,Esmenia C. Rocha,Leandro Marques de Souza,Mariana C. Pinho,Leonardo José Tadeu de Araújo,Frederico S V Malta,Aline B. de Lima,Joice do P. Silva,Danielle A G Zauli,Alessandro C. S. Ferreira,Ricardo P Schnekenberg,Daniel J Laydon,Patrick G T Walker,Hannah M. Schlüter,Ana L. P. dos Santos,Maria S. Vidal,Valentina S. Del Caro,Rosinaldo M. F. Filho,Helem M. dos Santos,Renato Santana Aguiar,José Luiz Proença Modena,Bruce Walker Nelson,James A. Hay,Melodie Monod,Xenia Miscouridou,Helen Coupland,Raphael Sonabend,Michaela A. C. Vollmer,Axel Gandy,Marc A. Suchard,Thomas A. Bowden,Sergei L Kosakovsky Pond,Chieh-Hsi Wu,Oliver Ratmann,Neil M. Ferguson,Christopher Dye,Nicholas J. Loman,Philippe Lemey,Andrew Rambaut,Nelson Abrahim Fraiji,Maria Perpétuo Socorro Sampaio Carvalho,Oliver G. Pybus,Oliver G. Pybus,Seth Flaxman,Samir Bhatt,Samir Bhatt,Ester Cerdeira Sabino +74 more
TL;DR: In this paper, the emergence and circulation of a new SARS-CoV-2 variant of concern, lineage P.1, that acquired 17 mutations, including a trio in the spike protein (K417T, E484K and N501Y) associated with increased binding to the human ACE2 receptor.
Data from: Evolution and epidemic spread of SARS-CoV-2 in Brazil
Darlan da Silva Candido,Ingra Morales Claro,Jaqueline Goes de Jesus,William Marciel de Souza,Filipe R. R. Moreira,Simon Dellicour,Thomas A. Mellan,Louis du Plessis,Rafael Henrique Moraes Pereira,Flavia C. S. Sales,Erika R. Manuli,Julien Thézé,Luiz Carlos de Almeida,Mariane Talon de Menezes,Carolina M. Voloch,Marcílio Jorge Fumagalli,Thais M. Coletti,Camila A. M. Silva,Mariana S. Ramundo,Mariene R. Amorim,Henrique Hoeltgebaum,Swapnil Mishra,Mandev S. Gill,Luiz Max Carvalho,Lewis F Buss,Carlos A. Prete,Jordan Ashworth,Helder I. Nakaya,Pedro S. Peixoto,Oliver J. Brady,Samuel M. Nicholls,Amilcar Tanuri,Átila Duque Rossi,Carlos Kaue Vieira Braga,Alexandra L. Gerber,Ana Paula de C Guimarães,Nelson Gaburo,Cecila Salete Alencar,Alessandro C. S. Ferreira,Cristiano Xavier Lima,José Eduardo Levi,Celso Francisco Hernandes Granato,Giulia M. Ferreira,Ronaldo da Silva Francisco,Fabiana Granja,Márcia Teixeira Garcia,Maria Luiza Moretti,Mauricio W. Perroud,Terezinha M. P. P. Castineiras,Carolina S. Lazari,Sarah C. Hill,Andreza Aruska de Souza Santos,Camila L. Simeoni,Julia Forato,Andrei C. Sposito,Angelica Zaninelli Schreiber,Magnun N. N. Santos,Camila Zolini de Sá,Renan P. Souza,Luciana C. Resende-Moreira,Mauro M. Teixeira,Josy Hubner,Patricia Asfora Falabella Leme,Rennan G. Moreira,Maurício Lacerda Nogueira,Neil M. Ferguson,Silvia Figueiredo Costa,José Luiz Proença-Módena,Ana Tereza Ribeiro de Vasconcelos,Samir Bhatt,Philippe Lemey,Chieh-Hsi Wu,Andrew Rambaut,Nicholas J. Loman,Renato Santana Aguiar,Oliver G. Pybus,Ester Cerdeira Sabino,Nuno R. Faria +77 more
TL;DR: New light is shed on the epidemic transmission and evolutionary trajectories of SARS-CoV-2 lineages in Brazil, and evidence that current interventions remain insufficient to keep virus transmission under control in the country is provided.
Posted ContentDOI
Evolution and epidemic spread of SARS-CoV-2 in Brazil
Darlan da Silva Candido,Ingra Morales Claro,Jaqueline Goes de Jesus,William Marciel de Souza,Filipe R. R. Moreira,Simon Dellicour,Thomas A. Mellan,Louis du Plessis,Rafael Henrique Moraes Pereira,Flavia C. S. Sales,Erika R. Manuli,Julien Thézé,Luiz Carlos de Almeida,Mariane Talon de Menezes,Carolina M. Voloch,Marcílio Jorge Fumagalli,Thais M. Coletti,Camila A. M. Silva,Mariana S. Ramundo,Mariene R. Amorim,Henrique Hoeltgebaum,Swapnil Mishra,Mandev S. Gill,Luiz Max Carvalho,Lewis F Buss,Carlos A. Prete,Jordan Ashworth,Helder I. Nakaya,Pedro S. Peixoto,Oliver J. Brady,Oliver J. Brady,Samuel M. Nicholls,Amilcar Tanuri,Átila Duque Rossi,Carlos Kaue Vieira Braga,Alexandra L. Gerber,Ana Paula de C Guimarães,Nelson Gaburo,Cecila Salete Alencar,Alessandro C. S. Ferreira,Cristiano Xavier Lima,José Eduardo Levi,Celso Francisco Hernandes Granato,Giula M. Ferreira,Ronaldo da Silva Francisco,Fabiana Granja,Márcia Teixeira Garcia,Maria Luiza Moretti,Mauricio W. Perroud,Terezinha M. P. P. Castineiras,Carolina S. Lazari,Sarah C. Hill,Andreza Aruska de Souza Santos,Camila L. Simeoni,Julia Forato,Andrei C. Sposito,Angelica Zaninelli Schreiber,Magnun N. N. Santos,Camila Zolini de Sá,Renan P. Souza,Luciana C. Resende-Moreira,Mauro M. Teixeira,Josy Hubner,Patricia Asfora Falabella Leme,Rennan G. Moreira,Maurício Lacerda Nogueira,CADDE-Genomic-Network,Neil M. Ferguson,Silvia Figueiredo Costa,José Luiz Proença-Módena,Ana Tereza Ribeiro de Vasconcelos,Samir Bhatt,Philippe Lemey,Chieh-Hsi Wu,Andrew Rambaut,Nicholas J. Loman,Renato Santana Aguiar,Oliver G. Pybus,Ester Cerdeira Sabino,Nuno R. Faria,Nuno R. Faria,Nuno R. Faria +81 more
TL;DR: Light is shed on the role of large and highly connected populated centres in the rapid ignition and establishment of SARS-CoV-2, and evidence that current interventions remain insufficient to keep virus transmission under control in Brazil is provided.