J
Julia Roensch
Researcher at Curie Institute
Publications - 4
Citations - 158
Julia Roensch is an academic researcher from Curie Institute. The author has contributed to research in topics: XIST & X-inactivation. The author has an hindex of 2, co-authored 4 publications receiving 81 citations. Previous affiliations of Julia Roensch include PSL Research University.
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Journal ArticleDOI
SPEN integrates transcriptional and epigenetic control of X-inactivation.
François Dossin,Inês Pinheiro,Jan J. Żylicz,Jan J. Żylicz,Julia Roensch,Samuel Collombet,Agnes Le Saux,Tomasz Chelmicki,Mikael Attia,Varun Kapoor,Ye Zhan,Florent Dingli,Damarys Loew,Thomas Mercher,Job Dekker,Job Dekker,Edith Heard +16 more
TL;DR: It is proposed that SPEN acts as a molecular integrator for the initiation of XCI, bridging Xist RNA with the transcription machinery—as well as with nucleosome remodellers and histone deacetylases—at active enhancers and promoters.
Journal ArticleDOI
H4K20me1 and H3K27me3 are concurrently loaded onto the inactive X chromosome but dispensable for inducing gene silencing.
Sjoerd J. D. Tjalsma,Mayako Hori,Yuko Sato,Aurelie Bousard,Akito Ohi,Ana Cláudia Raposo,Julia Roensch,Agnes Le Saux,Jumpei Nogami,Kazumitsu Maehara,Tomoya Kujirai,Tetsuya Handa,Sandra Bagés-Arnal,Yasuyuki Ohkawa,Hitoshi Kurumizaka,Simão Teixeira da Rocha,Jan J. Żylicz,Jan J. Żylicz,Jan J. Żylicz,Hiroshi Kimura,Edith Heard,Edith Heard +21 more
TL;DR: In this article, a genetically encoded, H3K27me3-specific intracellular antibody or H4K20me1-mintbody was developed to follow X chromosome inactivation (XCI) dynamics in living cells.
Posted ContentDOI
Tracking H3K27me3 and H4K20me1 dynamics during XCI reveals similarities in recruitment mechanism
Sjoerd J. D. Tjalsma,Mayako Hori,Yuko Sato,Aurelie Bousard,Akito Ohi,Ana Cláudia Raposo,Julia Roensch,Agnes Le Saux,Jumpei Nogami,Kazumitsu Maehara,Tomoya Kujirai,Yasuyuki Ohkawa,Hitoshi Kurumizaka,Simão Teixeira da Rocha,Jan J. Żylicz,Jan J. Żylicz,Hiroshi Kimura,Edith Heard +17 more
TL;DR: To follow XCI dynamics in living cells, a genetically-encoded, H3K27me3-specific intracellular antibody is developed and by combining it with live-imaging of H4K20me1, the X chromosome and Xist RNA, similarities in the initial accumulation dynamics are uncovered.
Posted ContentDOI
Tracking H3K27me3 and H4K20me1 during XCI reveals similarities in enrichment dynamics
Sjoerd J. D. Tjalsma,Mayako Hori,Yuko Sato,Aurelie Bousard,Akito Ohi,Ana Cláudia Raposo,Julia Roensch,Agnes Le Saux,Jumpei Nogami,Kazumitsu Maehara,Tomoya Kujirai,Tetsuya Handa,Sandra Bagés-Arnal,Yasuyuki Ohkawa,Hitoshi Kurumizaka,Simão Teixeira da Rocha,Jan J. Żylicz,Jan J. Żylicz,Jan J. Żylicz,Hiroshi Kimura,Edith Heard +20 more
TL;DR: In this article, a genetically-encoded, H3K27me3-specific intracellular antibody was developed and combined with live-imaging of H4K20me1, the X chromosome and Xist RNA.