Jumpei Nogami

TL;DR: An immunoprecipitation-free epigenomic profiling method named chromatin integration labelling (ChIL), which enables the amplification of genomic sequences closely associated with the target molecules before cell lysis and reliably detected the distributions of histone modifications and DNA-binding factors in 100–1,000 cells.

TL;DR: The crystal structure of the overlapping dinucleosome, in which two nucleosomes are associated, is reported, at 3.14-angstrom resolution, which may provide important information to understand how nucleosome repositioning occurs during the chromatin remodeling process.

TL;DR: It is found that mouse testis-specific and replication-dependent histone H3 variant H3t is essential for very early stages of spermatogenesis and male germ cells are able to enter meiosis and beyond.

TL;DR: It is found that MyoD expression was reduced at the mRNA level by cell cycle arrest in S and G2 phases, which in turn led to the absence of skeletal muscle differentiation.

TL;DR: In the developing zebrafish embryo, cell competition and elimination of unfit cells are required for proper Wnt gradient formation, which may support tissue robustness and disease prevention.