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Julien Nicolas

Researcher at Université Paris-Saclay

Publications -  149
Citations -  17518

Julien Nicolas is an academic researcher from Université Paris-Saclay. The author has contributed to research in topics: Polymerization & Copolymer. The author has an hindex of 51, co-authored 137 publications receiving 15150 citations. Previous affiliations of Julien Nicolas include Arkema & University of Warwick.

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Nitroxide-Mediated Polymerization of Vinyl Chloride at Low Temperature: Kinetic and Computational Studies

TL;DR: In this paper, the synthesis of polyvinyl chloride (PVC) by nitroxide-mediated polymerization (NMP) using the SG1-based BlocBuilder alkoxyamine at low temperature (30 and 42 °C) is reported.
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Facile synthesis of multicompartment micelles based on biocompatible poly(3-hydroxyalkanoate).

TL;DR: After nanoprecipitation in water, novel PHA-based MCMs are evidenced by cryo-transmission electron microscopy and the cytocompatibility of MCMs is demonstrated in vitro via cell viability assay.
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PEGylation and preliminary biocompatibility evaluation of magnetite–silica nanocomposites obtained by high energy ball milling

TL;DR: By cell viability (MTT) assays and cell morphology investigations, it was evidenced that PEGylated Fe(3)O(4)-SiO(2) nanocomposites did not provide any appreciable cytotoxicity on J774 macrophage and MCF-7 breast cancer cell lines.
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Effect of nanoparticles binding β-amyloid peptide on nitric oxide production by cultured endothelial cells and macrophages

TL;DR: Liposomal and PEG-PACA nanoparticles have a limited effect on vascular homeostasis and inflammatory response, rendering them potentially suitable for treatment of Alzheimer’s disease.
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Degradable polymer prodrugs with adjustable activity from drug-initiated radical ring-opening copolymerization.

TL;DR: Degradable polymer prodrugs were synthesized by ‘drug-initiated’ nitroxide-mediated radical ring-opening copolymerization and led to either nanoparticles or solubleProdrugs with adjustable cytotoxicity on two different cancer cell lines.