Jungmin Lee

TL;DR: A microfluidic approach to delivery in which cells are mechanically deformed as they pass through a constriction 30–80% smaller than the cell diameter results in the formation of transient holes that enable the diffusion of material from the surrounding buffer into the cytosol.

TL;DR: Any design of nanoparticle vectors for cancer therapy or imaging must take into account the interaction of the nanoparticles with the tumor microenvironment, and size, charge, and shape have been shown to dominate this interaction.

TL;DR: In this paper, the interaction of the nanoparticles with the tumor microenvironment has been studied, and size, charge, and shape have been shown to dominate the interaction between nanoparticles and the microenvironment.

TL;DR: In this article, a new class of polymeric ligands for quantum dot (QD) water solubilization was proposed to yield biocompatible and derivatizable QDs with compact size (∼10−12 nm diameter), high quantum yields (>50%), excellent stability across a large pH range (pH 5−105), and low nonspecific binding.