J
Junko Hirose
Researcher at University of Shiga Prefecture
Publications - 16
Citations - 897
Junko Hirose is an academic researcher from University of Shiga Prefecture. The author has contributed to research in topics: Bifidobacterium longum & Vitamin. The author has an hindex of 9, co-authored 14 publications receiving 681 citations.
Papers
More filters
Journal ArticleDOI
Physiology of Consumption of Human Milk Oligosaccharides by Infant Gut-associated Bifidobacteria
Sadaki Asakuma,Emi Hatakeyama,Tadasu Urashima,Erina Yoshida,Takane Katayama,Kenji Yamamoto,Hidehiko Kumagai,Hisashi Ashida,Junko Hirose,Motomitsu Kitaoka +9 more
TL;DR: Interestingly, B. bifidum left degraded HMO metabolites outside of the cell even when the cells initiate vegetative growth, which indicates that the different species/subspecies can share the produced sugars.
Journal ArticleDOI
Sharing of human milk oligosaccharides degradants within bifidobacterial communities in faecal cultures supplemented with Bifidobacterium bifidum.
Aina Gotoh,Toshihiko Katoh,Mikiyasu Sakanaka,Yiwei Ling,Chihaya Yamada,Sadaki Asakuma,Tadasu Urashima,Yusuke Tomabechi,Ayako Katayama-Ikegami,Shin Kurihara,Kenji Yamamoto,Gaku Harata,Fang He,Junko Hirose,Motomitsu Kitaoka,Shujiro Okuda,Takane Katayama,Takane Katayama +17 more
TL;DR: This study observed altruistic behaviour by B. bifidum when incubated in HMOs-containing faecal cultures and determined the complete genome sequences of B.bifidUM strains JCM7004 and TMC3115, which suggest B. fidum-mediated cross-feeding of H MOs degradants within b ifidobacterial communities.
Journal ArticleDOI
Bifidobacterium longum subsp. infantis uses two different β-galactosidases for selectively degrading type-1 and type-2 human milk oligosaccharides
Erina Yoshida,Haruko Sakurama,Masashi Kiyohara,Masahiro Nakajima,Motomitsu Kitaoka,Hisashi Ashida,Junko Hirose,Takane Katayama,Kenji Yamamoto,Hidehiko Kumagai +9 more
TL;DR: In this paper, the authors characterized β-galactosidases of Bifidobacterium longum subsp. infantis to understand how the organism degrades type-1 (Galβ1-3GlcNAc) and type-2 isomers of HMOs.
Journal ArticleDOI
Evolutionary adaptation in fucosyllactose uptake systems supports bifidobacteria-infant symbiosis.
Mikiyasu Sakanaka,Morten Ejby Hansen,Aina Gotoh,Toshihiko Katoh,Keisuke Yoshida,Toshitaka Odamaki,Hiroyuki Yachi,Yuta Sugiyama,Shin Kurihara,Junko Hirose,Tadasu Urashima,Jin-zhong Xiao,Motomitsu Kitaoka,Satoru Fukiya,Atsushi Yokota,Leila Lo Leggio,Maher Abou Hachem,Takane Katayama,Takane Katayama +18 more
TL;DR: This work characterized two functionally distinct but overlapping fucosyllactose transporters from Bifidobacterium longum subspecies infantis and provided a molecular insight into HMO-mediated symbiosis and coevolution between b ifidobacteria and humans.
Journal ArticleDOI
Molecular Insight into Evolution of Symbiosis between Breast-Fed Infants and a Member of the Human Gut Microbiome Bifidobacterium longum
Chihaya Yamada,Chihaya Yamada,Aina Gotoh,Mikiyasu Sakanaka,Mitchell Hattie,Keith A. Stubbs,Ayako Katayama-Ikegami,Junko Hirose,Shin Kurihara,Takatoshi Arakawa,Motomitsu Kitaoka,Shujiro Okuda,Takane Katayama,Takane Katayama,Shinya Fushinobu +14 more
TL;DR: It is shown that lnbX is indispensable for B. longum growth on lacto-N-tetraose and is a key genetic factor for persistence in the gut of breast-fed infants.