K
Karen Broughton
Researcher at Public Health England
Publications - 14
Citations - 1055
Karen Broughton is an academic researcher from Public Health England. The author has contributed to research in topics: Population & Streptococcus pneumoniae. The author has an hindex of 11, co-authored 13 publications receiving 822 citations. Previous affiliations of Karen Broughton include Health Protection Agency.
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Journal ArticleDOI
Genetic Relationships between Clinical Isolates of Streptococcus pneumoniae, Streptococcus oralis, and Streptococcus mitis: Characterization of “Atypical” Pneumococci and Organisms Allied to S. mitis Harboring S. pneumoniae Virulence Factor-Encoding Genes
Adrian M. Whatmore,Androulla Efstratiou,A. P. Pickerill,Karen Broughton,G Woodard,D Sturgeon,R C George,Christopher G. Dowson +7 more
TL;DR: A number of potentially important pathogenic isolates, which were frequently associated with respiratory disease, were identified that phenotypically and genetically are most closely related to S. pneumoniae, S. mitis, and S. oralis.
Journal ArticleDOI
Changes in the incidence of invasive disease due to Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria meningitidis during the COVID-19 pandemic in 26 countries and territories in the Invasive Respiratory Infection Surveillance Initiative: a prospective analysis of surveillance data.
Angela B. Brueggemann,Melissa J. Jansen van Rensburg,David Shaw,Noel D. McCarthy,Keith A. Jolley,Martin C. J. Maiden,Mark van der Linden,Zahin Amin-Chowdhury,Desiree E. Bennett,Ray Borrow,Maria Cristina C. Brandileone,Karen Broughton,Ruth Campbell,Bin Cao,Carlo Casanova,Eun Hwa Choi,Yiu Wai Chu,Stephen Clark,Heike Claus,Juliana Coelho,Mary Corcoran,Mary Corcoran,Simon Cottrell,Robert Cunney,Robert Cunney,Tine Dalby,Heather Davies,Linda de Gouveia,Ala Eddine Deghmane,Walter Demczuk,Stefanie Desmet,Richard J. Drew,Richard J. Drew,Mignon du Plessis,Helga Erlendsdóttir,Norman K. Fry,Kurt Fuursted,Steve J. Gray,Birgitta Henriques-Normark,Thomas Hale,Markus Hilty,Steen Hoffmann,Hilary Humphreys,Margaret Ip,Susanne Jacobsson,Jillian Johnston,Jana Kozakova,Karl G. Kristinsson,Pavla Krizova,Alicja Kuch,Shamez N Ladhani,Thiên Trí Lâm,Vera Lebedova,Laura Lindholm,David Litt,Irene Martin,Delphine Martiny,Wesley Mattheus,Martha McElligott,Mary Meehan,Susan Meiring,Paula Mölling,Eva Morfeldt,Julie Morgan,Robert M. Mulhall,Carmen Muñoz-Almagro,David R. Murdoch,Joy Murphy,Martin Musilek,Alexandre Mzabi,Amaresh Perez-Argüello,Monique Perrin,Malorie Perry,Alba Redin,Richard J. Roberts,Maria Roberts,Assaf Rokney,Merav Ron,Kevin J. Scott,Carmen L. Sheppard,Lotta Siira,Anna Skoczynska,Monica Sloan,Hans Christian Slotved,Andrew Smith,Joon Young Song,Muhamed-Kheir Taha,Maija Toropainen,Dominic N.C. Tsang,Anni Vainio,Nina M. van Sorge,Emmanuelle Varon,Jiri Vlach,Ulrich Vogel,Sandra Vohrnova,Anne von Gottberg,Rosemeire C. Zanella,Fei Zhou +97 more
TL;DR: In this article, the authors investigated the incidence of invasive disease due to these pathogens during the early months of the COVID-19 pandemic and found that containment policies and public information campaigns likely reduced transmission of S pneumoniae, H influenzae, and N meningitidis, leading to a significant reduction in lifethreatening invasive diseases in many countries worldwide.
Journal ArticleDOI
Emerging Trends in the Epidemiology of Invasive Group B Streptococcal Disease in England and Wales, 1991–2010
Theresa Lamagni,Catherine Keshishian,Androulla Efstratiou,Rebecca Guy,Katherine Henderson,Karen Broughton,Elizabeth Sheridan +6 more
TL;DR: Although risk of invasive GBS infection remains highest within the first few days of life, the relative burden of disease is shifting toward adults, and the rise in incidence and antibiotic resistance makes development of an effective and safe vaccine all the more pressing.
Journal ArticleDOI
Invasive Pneumococcal Disease in England and Wales: Vaccination Implications
Karen Sleeman,Kyle Knox,Kyle Knox,Robert George,Elizabeth L. Miller,Pauline Waight,David Griffiths,A Efstratiou,Karen Broughton,Richard T. Mayon-White,E. R. Moxon,Derrick W. Crook +11 more
TL;DR: The data indicate that IPD varies by serotype, age, and country, emphasizing that the epidemiology of IPD is heterogeneous and requires continued surveillance.
Journal ArticleDOI
Identification of Three Novel Superantigen-Encoding Genes in Streptococcus equi subsp. zooepidemicus, szeF, szeN, and szeP
Romain Paillot,Alistair C. Darby,Carl Robinson,N. Wright,Karen F. Steward,Emma L Anderson,Emma L Anderson,K. Webb,Matthew T. G. Holden,Androulla Efstratiou,Karen Broughton,Keith A. Jolley,Simon L. Priestnall,Maria C. Marotti Campi,Margaret Hughes,Alan D Radford,Kerstin Erles,Andrew S. Waller +17 more
TL;DR: It is concluded that horizontal transfer of these novel superantigens from and within the diverse S. equi subsp.