K
Katayoon Pakravan
Researcher at Tarbiat Modares University
Publications - 14
Citations - 388
Katayoon Pakravan is an academic researcher from Tarbiat Modares University. The author has contributed to research in topics: Endothelial stem cell & Cancer. The author has an hindex of 6, co-authored 12 publications receiving 226 citations.
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Journal ArticleDOI
MicroRNA-100 shuttled by mesenchymal stem cell-derived exosomes suppresses in vitro angiogenesis through modulating the mTOR/HIF-1α/VEGF signaling axis in breast cancer cells.
Katayoon Pakravan,Sadegh Babashah,Majid Sadeghizadeh,Seyed Javad Mowla,Majid Mossahebi-Mohammadi,Farangis Ataei,Nasim Dana,Mohammad Javan,Mohammad Javan +8 more
TL;DR: The findings suggest that exosomal transfer of miR-100 may be a novel mechanism underlying the paracrine effects of MSC-derived exosomes and may provide a means by which these vesicles can modulate vascular responses within the microenvironment of breast cancer cells.
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Novel strategies for targeting leukemia stem cells: sounding the death knell for blood cancer
Antonieta Chávez-González,Babak Bakhshinejad,Katayoon Pakravan,Monica L. Guzman,Sadegh Babashah +4 more
TL;DR: A growing body of evidence indicates that the selective targeting of LSCs represents a promising approach to improve disease outcome, and the CSC hypothesis has added a new dimension to the area of anticancer research, thereby paving the way for shaping a new trend in cancer therapy.
Journal ArticleDOI
A panel of six-circulating miRNA signature in serum and its potential diagnostic value in colorectal cancer
Hamidreza Maminezhad,Sharareh Ghanadian,Katayoon Pakravan,Ehsan Razmara,Fatemeh Rouhollah,Majid Mossahebi-Mohammadi,Sadegh Babashah +6 more
TL;DR: It is confirmed that serum-derived miRNAs have a strong potential to be a diagnostic biomarker for patients with CRC, and were significantly up-regulated in CRC patients, while miR-143 and mi-145 showed a significant down-regulation.
Journal Article
Therapeutic application of mesenchymal stem cell-derived exosomes: A promising cell-free therapeutic strategy in regenerative medicine.
Mahsa Motavaf,Katayoon Pakravan,Sadegh Babashah,F Malekvandfard,Mahbobeh Masoumi,Majid Sadeghizadeh +5 more
TL;DR: The current literature on administration of exosomes released by mesenchymal stem cells in regenerative medicine is summarized and how they could help to improve tissue regeneration following injury is suggested.
Journal ArticleDOI
Colorectal cancer cell-derived extracellular vesicles transfer miR-221-3p to promote endothelial cell angiogenesis via targeting suppressor of cytokine signaling 3.
Maryam Dokhanchi,Katayoon Pakravan,Sara Zareian,Bashdar Mahmud Hussen,Mahsa Farid,Ehsan Razmara,Majid Mossahebi-Mohammadi,William C. Cho,Sadegh Babashah +8 more
TL;DR: In this paper, the authors evaluated the potential clinical significance of a signature of four circulating serum-derived miRNAs in colorectal cancer patients and demonstrated that extracellular vesicles (EVs) containing miR-221-3p could facilitate endothelial cell angiogenesis.