K
Katja Salomon Johansen
Researcher at University of Copenhagen
Publications - 79
Citations - 4047
Katja Salomon Johansen is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Cellulose & Cellulase. The author has an hindex of 26, co-authored 72 publications receiving 3279 citations. Previous affiliations of Katja Salomon Johansen include Chalmers University of Technology & Technical University of Denmark.
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Journal ArticleDOI
Insights into the oxidative degradation of cellulose by a copper metalloenzyme that exploits biomass components
R. Jason Quinlan,Matthew Sweeney,Leila Lo Leggio,Harm Otten,Jens-Christian N. Poulsen,Katja Salomon Johansen,Kristian B. R. M. Krogh,Christian Isak Jørgensen,Morten Tovborg,Annika Anthonsen,Theodora Tryfona,Clive P. Walter,Paul Dupree,Feng Xu,Gideon J. Davies,Paul H. Walton +15 more
TL;DR: It is demonstrated that copper is needed for GH61 maximal activity and that the formation of cellodextrin and oxidized cellodesxtrin products by GH61 is enhanced in the presence of small molecule redox-active cofactors such as ascorbate and gallate.
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Structure and boosting activity of a starch-degrading lytic polysaccharide monooxygenase
Leila Lo Leggio,Thomas J. Simmons,Jens-Christian N. Poulsen,Kristian E. H. Frandsen,Glyn R. Hemsworth,Mary Ann Stringer,Pernille von Freiesleben,Morten Tovborg,Katja Salomon Johansen,Leonardo De Maria,Leonardo De Maria,Paul Harris,Chee Leong Soong,Paul Dupree,Theodora Tryfona,Nicolas Lenfant,Bernard Henrissat,Bernard Henrissat,Gideon J. Davies,Paul H. Walton +19 more
TL;DR: It is demonstrated that these enzymes generate aldonic acid-terminated malto-oligosaccharides from retrograded starch and boost significantly the conversion of this recalcitrant substrate to maltose by β-amylase.
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The molecular basis of polysaccharide cleavage by lytic polysaccharide monooxygenases
Kristian E. H. Frandsen,Thomas J. Simmons,Paul Dupree,Jens-Christian N. Poulsen,Glyn R. Hemsworth,Luisa Ciano,Esther M. Johnston,Morten Tovborg,Katja Salomon Johansen,Pernille von Freiesleben,Laurence Marmuse,Sébastien Fort,Sylvain Cottaz,Hugues Driguez,Bernard Henrissat,Bernard Henrissat,Bernard Henrissat,Nicolas Lenfant,Nicolas Lenfant,Floriana Tuna,Amgalanbaatar Baldansuren,Gideon J. Davies,Leila Lo Leggio,Paul H. Walton +23 more
TL;DR: A structural determination of an LPMO-oligosaccharide complex is reported, yielding detailed insights into the mechanism of action of these enzymes.
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Spectroscopic and computational insight into the activation of O2 by the mononuclear Cu center in polysaccharide monooxygenases
Christian H. Kjaergaard,Munzarin F. Qayyum,Shaun D. Wong,Feng Xu,Glyn R. Hemsworth,Daniel J. Walton,Nigel A. Young,Gideon J. Davies,Paul H. Walton,Katja Salomon Johansen,Keith O. Hodgson,Britt Hedman,Edward I. Solomon +12 more
TL;DR: The solution structures of both the reduced and oxidized Cu site are determined, and it is determined how this site is capable of facile O2 activation by a thermodynamically difficult one-electron reduction, via an inner-sphere Cu-superoxide intermediate.
Journal ArticleDOI
Harnessing the potential of LPMO-containing cellulase cocktails poses new demands on processing conditions
Gerdt Müller,Anikó Várnai,Katja Salomon Johansen,Katja Salomon Johansen,Vincent G. H. Eijsink,Svein Jarle Horn +5 more
TL;DR: A direct correlation between saccharification yield and LPMO activity of commercial enzyme cocktails is demonstrated, which shows that the L PMO contribution to overall efficiency may be large if process conditions are adapted to the key determinants of LPMOs activity, namely the presence of electron donors and molecular oxygen.