Kavita Shah

TL;DR: The identities of these substrates reveal that Cdk1 employs a global regulatory strategy involving phosphorylation of other regulatory molecules as well as phosphorylated of the molecular machines that drive cell-cycle events.

TL;DR: The development of a protein engineering-based method to identify the direct substrates of the prototypical protein tyrosine kinase v-Src, which controls fibroblast transformation by the Rous sarcoma virus, is described.

TL;DR: The speed and specificity of inhibition suggests that myosin-1c participates in adaptation in hair cells, the sensory cells of the inner ear.

TL;DR: The role of MAPK/ERK is established in phosphorylation-dependent cellular localization of hnRNP-K, which is required for its ability to silence mRNA translation.

TL;DR: In vivo treatment of human repopulating cells with Wnt-5A CM produced a greater proportion of phenotypically primitive hematopoietic progeny that could be isolated and shown to possess enhanced progenitor function independent of continued Wnt -5A treatment, suggesting a potential role for activation of Wnt signaling in managing patients exhibiting poor hematoplastic recovery shortly after stem cell transplantation.