K
Kazuo Nagasawa
Researcher at Tokyo University of Agriculture and Technology
Publications - 329
Citations - 6484
Kazuo Nagasawa is an academic researcher from Tokyo University of Agriculture and Technology. The author has contributed to research in topics: Enantioselective synthesis & Catalysis. The author has an hindex of 40, co-authored 311 publications receiving 5777 citations. Previous affiliations of Kazuo Nagasawa include Harvard University & University of Tokyo.
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G-quadruplex dna detection probe and method for detecting g-quadruplex structure using the same
TL;DR: In this paper, a G-quadruplex DNA detection probe, a method for detecting a G quadruplex structure including the detection of the probe which is bound with a genome DNA or its segments by bringing the probe into contact with the subject DNA or segments, and a method to screening a G quadruplex-bound substance including the screening of the substance which increases or reduces the expression of the gene bound with and positioned in the vicinity of the detected in the above method.
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Organocatalytic Asymmetric Nitroaldol Reaction: Cooperative Effects of Guanidine and Thiourea Functional Groups.
Yoshihiro Sohtome,Nobuko Takemura,Keisuke Takada,Rika Takagi,Toshitsugu Iguchi,Kazuo Nagasawa +5 more
TL;DR: In this paper, a guanidine-thiourea cooperative mechanism and a transition state of the catalytic reactions are proposed, on the basis of studies of structure and catalytic-activity relationships.
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Synthesis of (+)‐Batzelladine K (I).
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Vinylnaphthalene-bearing hexaoxazole as a fluorescence turn-on type G-quadruplex ligand.
Yue Ma,Yuki Wakabayashi,Naruyuki Watatani,Ryota Saito,Takatsugu Hirokawa,Takatsugu Hirokawa,Masayuki Tera,Kazuo Nagasawa +7 more
TL;DR: In this article, a stilbene-type fluorophore, MO-VN (1), consisting of a mono oxazole bearing a vinyl naphthalene moiety, was embedded in a trioxazole 2 and a cyclic hexaoxazoles 3a.
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Nontoxic Enantiomeric Reference Materials for Saxitoxins.
Ryuichi Watanabe,Yuka Takayanagi,Osamu Chiba,Shota Itoda,Hayate Ishizuka,Minami Odagi,Mayuko Ozawa,Hajime Uchida,Ryoji Matsushima,Keiichi Konoki,Mari Yotsu-Yamashita,Kazuo Nagasawa,Toshiyuki Suzuki +12 more
TL;DR: In this paper , the authors proposed a method to avoid violation of the Chemical Weapons Convention and facilitate analyses by preparing calibration standards based on unnatural nontoxic antipodal Saxitoxin (ent-STXs) with the same physicochemical properties as natural STXs.