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Keith A. Cengel
Researcher at University of Pennsylvania
Publications - 210
Citations - 12705
Keith A. Cengel is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Lung cancer & Medicine. The author has an hindex of 34, co-authored 178 publications receiving 10610 citations. Previous affiliations of Keith A. Cengel include University of Illinois at Urbana–Champaign & Hospital of the University of Pennsylvania.
Papers
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Journal ArticleDOI
Monte Carlo modeling in CT-based geometries: dosimetry for biological modeling experiments with particle beam radiation
Eric S. Diffenderfer,Derek Dolney,Maximilian Schaettler,Jenine K. Sanzari,James McDonough,Keith A. Cengel +5 more
TL;DR: The software developed and validated in this study represents a critically important new tool that allows integration of computational and biological modeling for evaluating the biological outcomes of exposures to inhomogeneous SPE-like radiation dose distributions, and has potential applications for other environmental and therapeutic exposure simulations.
Journal ArticleDOI
Lymphangitic carcinomatosis: A common radiographic manifestation of local failure following extended pleurectomy/decortication in patients with malignant pleural mesothelioma.
Ian Berger,Keith A. Cengel,Charles B. Simone,Evan W. Alley,Leonid Roshkovan,Andrew R. Haas,Akash M. Patel,Urooj Khalid,Melissa Culligan,Sally McNulty,Sunil Singhal,Joseph S. Friedberg,Sharyn I. Katz +12 more
TL;DR: LC is a common form of failure in MPM following EPD and is associated with a poor prognosis, and further studies are warranted to determine if any evidence of preoperative LC should be an absolute contraindication to E PD and may warrant an EPP or no surgery at all.
Journal ArticleDOI
In vivo Spectroscopic Evaluation of the Intraperitoneal Cavity in Canines.
Gwendolyn M. Cramer,Julia Sandell Meo,Jarod C. Finlay,Timothy C. Zhu,Theresa M. Busch,Keith A. Cengel +5 more
TL;DR: Hemoglobin concentration, oxygenation and optical properties were determined to be highly heterogeneous between canines and at different anatomical locations within the same subject, so further development of PDT dosimetry systems will need to address this patient and location‐specific dose optimization.
Proceedings ArticleDOI
A heterogeneous optimization algorithm for reacted singlet oxygen for interstitial PDT
Timothy C. Zhu,Martin D. Altschuler,Yida Hu,Ken Wang,Jarod C. Finlay,Andreea Dimofte,Keith A. Cengel,Stephen M. Hahn +7 more
TL;DR: The study shows that optimization of individual light source positions and intensities is feasible for the heterogeneous prostate during PDT.
Proceedings ArticleDOI
Definitive surgery and intraoperative photodynamic therapy: a prospective study of local control and survival for patients with pleural dissemination of non-small cell lung cancer.
TL;DR: This is the first ever report describing optimal methods, techniques, and dosimetry that could be used to safely and reproducibly deliver intraoperative PDT to the chest cavity as part of multimodality therapy for NSCLC with pleural metastasis.